Improved traditional medicine for infectious disorders in Mali

Sanogo, Rokia; Haïdara, Mahamane; Dénou, Adama

doi:10.1016/b978-0-323-90999-0.00004-5

Cited by 4 publications

(1 citation statement)

References 45 publications

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“…The NRITMP's research has resulted in seven Improved Traditional Medicines (ITMs) being placed on the Malian market and included in the National List of Essential Medicines (NLEM), while other marketing authorization (MA) applications are underway. (5,22,23) ITMs are medicines derived from TM recipes, with quantified dosages, defined toxicity limits, confirmed efficacy and controlled quality. Their development involves ethnobotanical surveys and phytochemical, toxicological, pharmacological, galenical and clinical studies.…”

Section: Introductionmentioning

confidence: 99%

Experience of Health professionals in the implementation of Clinical trials of Traditional Herbal Medicines: A cross-sectional study in Mali

SANGHO,

Dori,

Ouoba

et al. 2024

Int J Drug Reg Affairs

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Objective: The objective of this study was to determine the experience of health professionals in clinical trials of traditional herbal medicines in Mali. Material and methods: This was a cross-sectional study conducted from June to December 2022 among healthcare professionals in three randomly selected localities: the district of Bamako and the regions of Koulikoro and Sikasso. Data were collected by direct interview using an anonymous questionnaire. The Chi-square (χ2) test was used to assess factors associated with participation in clinical trials of traditional medicines. Results: The involvement of healthcare professionals in clinical trials of traditional medicines was low (3.5%) and was associated with age (p=0.021). The obstacles to conducting these trials reported by healthcare professionals were lack of funding and failure to take account of the specificities of traditional medicines in clinical trial regulations. Some healthcare professionals suggest ethnomedical evaluation of recipes proposed by traditional practitioners and the use of reverse pharmacology as alternatives. Conclusion: Research into traditional medicines could be given greater impetus by the long-term funding of clinical trials and by less costly alternatives such as the ethnomedical evaluation of recipes proposed by traditional healers and reverse pharmacology.

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Section: Introductionmentioning

confidence: 99%

Experience of Health professionals in the implementation of Clinical trials of Traditional Herbal Medicines: A cross-sectional study in Mali

SANGHO,

Dori,

Ouoba

et al. 2024

Int J Drug Reg Affairs

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Contribution of Ethnomedical Use Data to the Marketing Authorization of Traditional Herbal Medicines in Mali

Sangho,

Ouoba,

Semdé

et al. 2024

Global Advances in Integrative Medicine and Health

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Background To improve the supply of health care and health care products, traditional herbal medicines that are safe, effective, and of good quality need marketing authorizations. This study aims to determine the contribution of ethnomedical evidence to the marketing of traditional herbal medicines in Mali. Methods This was a descriptive cross-sectional study conducted from December 2023 to March 2024 supplemented by a literature review of the legislative and regulatory provisions relating to traditional medicine and the requirements for marketing authorization of traditional herbal medicines in Mali and the West African sub-region. Results The regulatory framework for marketing authorization is governed by decree no. 04-557/P-RM of 01 December 2004 and interministerial order no. 05-2203/MS-MEP-SG of 20 September 2005 in Mali. These texts set out the specific requirements for the marketing authorization of traditional plant-based medicines, depending on the category. They consider ethnomedical evidence drawn from long experience of traditional use as proof of efficacy and tolerance for category 2 traditional medicines. As a result, marketing authorizations were issued for 15 products derived from traditional medicine and pharmacopeia, 5 of which are included in the National List of Essential Medicines and the National Therapeutic Formulary of Mali. Conclusion The use of ethnomedical evidence provides a good opportunity to obtain marketing authorization for phytomedicines derived from traditional medicine without having to go through long and costly non-clinical and clinical studies.

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African Traditional Medicine as a COVID-19 treatment and the South African Government response

Bhuda,

Mdhluli

2024

pharosjot

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As South Africa faced the new dawn of COVID-19 pandemic, questions were raised regarding the utilization of African traditional medicine as a treatment of the illness. Madagascar was viewed by African people as a pioneer to regard and declare Artemisia as treatment for COVID-19 and developed products known as Africa following its breakthrough in traditional herbal cure for COVID-19 known as COVID Organics or CVO to be used by their citizens and the rest of African states. In July 2020, the World Health Organization (WHO) and the Africa Centres for Disease Control and Prevention formed a Regional Expert Committee on Conventional Medicine for COVID-19 in an attempt to enhance research and development of traditional medicines such as CVO, aiming to test traditional therapies and provide independent advice on their safety and efficacy. However, six months after its formation, it appeared that this attempt to regulate has failed to gain traction: None of the proposed remedies progressed beyond phase II clinical trials. Using existing secondary sources such as articles, government documents and media releases, this paper aims to look at the response from South African government on utilization of African Traditional Medicine as COVID-19 treatment. A special attention is given to South African government’s response to the treatment proposed by the state of Madagascar and its way forward towards using traditional medicine as treatment to COVID-19.

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Improved traditional medicine for infectious disorders in Mali

Cited by 4 publications

References 45 publications

Experience of Health professionals in the implementation of Clinical trials of Traditional Herbal Medicines: A cross-sectional study in Mali

Experience of Health professionals in the implementation of Clinical trials of Traditional Herbal Medicines: A cross-sectional study in Mali

Contribution of Ethnomedical Use Data to the Marketing Authorization of Traditional Herbal Medicines in Mali

African Traditional Medicine as a COVID-19 treatment and the South African Government response

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