Improved viability of latissimus dorsi muscle grafts after electrical prestimulation

Woo, E.; Tang, Augustine; Jarvis, Jonathan C.; Hasleton, Philip; Salmons, Stanley; Hooper, Timothy L.

doi:10.1002/mus.10099

Cited by 11 publications

(7 citation statements)

References 32 publications

(78 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Muscles can adapt to altered functional demands by changing the fiber cross-sectional area and their MyHC-type composition. Long-term electrical stimulation of the skeletal muscle has been demonstrated to cause an increase in the percentage of slow-type fatigueresistant fibers (Kernell et al 1987;Caiozzo, 2002;Woo et al 2002;Pae et al 2007) and cross-sectional area of muscle fibers (Delp & Pette, 1994). Inactivity of the muscle is followed by an increase in fast-type fibers and decrease in the fiber cross-sections (Grossman et al 1998).…”

Section: Introductionmentioning

confidence: 99%

Adaptation of rat jaw muscle fibers in postnatal development with a different food consistency: an immunohistochemical and electromyographic study

et al. 2010

View full text Add to dashboard Cite

The development of the craniofacial system occurs, among other reasons, as a response to functional needs. In particular, the deficiency of the proper masticatory stimulus affects the growth. The purpose of this study was to relate alterations of muscle activity during postnatal development to adaptational changes in the muscle fibers. Fourteen 21-day-old Wistar strain male rats were randomly divided into two groups and fed on either a solid (hard-diet group) or a powder (soft-diet group) diet for 63 days. A radio-telemetric device was implanted to record muscle activity continuously from the superficial masseter, anterior belly of digastric and anterior temporalis muscles. The degree of daily muscle use was quantified by the total duration of muscle activity per day (duty time), the total burst number and their average length exceeding specified levels of the peak activity (5, 20 and 50%). The fiber type composition of the muscles was examined by the myosin heavy chain content of fibers by means of immunohistochemical staining and their cross-sectional area was measured. All muscle fibers were identified as slow type I and fast type IIA, IIX or IIB (respectively, with increasing twitch contraction speed and fatigability). At lower activity levels (exceeding 5% of the peak activity), the duty time of the anterior belly of the digastric muscle was significantly higher in the soft-diet group than in the hard-diet group (P < 0.05). At higher activity levels (exceeding 20 and 50% of the peak activity), the duty time of the superficial masseter muscle in the soft-diet group was significantly lower than that in the hard-diet group (P < 0.05). There was no difference in the duty time of the anterior temporalis muscle at any muscle activity level. The percentage of type IIA fibers of the superficial masseter muscle in the soft-diet group was significantly lower than that in the hard-diet group (P < 0.01) and the opposite was true with regard to type IIB fibers (P < 0.05). The crosssectional area of type IIX and type IIB fibers of the superficial masseter muscle was significantly smaller in the soft-diet group than in the hard-diet group (P < 0.05). There was no difference in the muscle fiber composition and the cross-sectional area of the anterior belly of the digastric and anterior temporalis muscles. In conclusion, for the jaw muscles of male rats reared on a soft diet, the slow-to-fast transition of muscle fiber was shown in only the superficial masseter muscle. Therefore, the reduction in the amount of powerful muscle contractions could be important for the slow-to-fast transition of the myosin heavy chain isoform in muscle fibers.

show abstract

Section: Introductionmentioning

confidence: 99%

Adaptation of rat jaw muscle fibers in postnatal development with a different food consistency: an immunohistochemical and electromyographic study

et al. 2010

View full text Add to dashboard Cite

show abstract

“…It then perfuses the whole of the grafted muscle [89,90]. This is associated with enhanced muscle function and viability [42,91].…”

Section: Prestimulationmentioning

confidence: 99%

Cardiac assistance from skeletal muscle: a reappraisal☆

Salmons

2009

European Journal of Cardio-Thoracic Surgery

Self Cite

View full text Add to dashboard Cite

SummaryCardiac assistance from skeletal muscle offers an attractive surgical solution to the problem of end-stage heart failure, yet it is widely regarded as a failed approach. I argue here that this is an outdated assessment. Systematic progress has been made over the last 25 years in understanding the relevant basic science. In the light of these advances we should be reconsidering the place of skeletal muscle assist in the surgical armamentarium. #

show abstract

“…Recent studies in rat and pig latissimus dorsi models demonstrate peripheral muscle damage as a consequence distal ischaemia secondary to mobilisation, but less if muscles were pre-conditioned. 26,27 The rabbit tibialis anterior model, though useful for electrical conditioning studies, [18][19][20][21][22] is suboptimal in respect of its pattern of blood supply: 12,28 ultimately, only human studies will provide reliable data.…”

Section: Measurements In Muscles In Situ and Mobilised As Flapsmentioning

confidence: 99%

The nutrition of active muscle flaps

Greenbaum¹

2005

Ann R Coll Surg Engl

View full text Add to dashboard Cite

In the last 25 years, techniques utilising muscle flaps to perform mechanical work have become part of the reconstructive surgeon's repertoire. In this paper, these techniques and the particular physiological challenges faced by active flaps are discussed and a sub-classification of muscle flaps into passive and active is proposed. A series of experiments are described that were designed to compare local pO 2 and gaseous perfusion, at multiple sites in pedicled tibialis anterior muscle flaps and controls, using specially developed dual amperometric microelectrodes, in an in vivo rabbit model. No significant difference in perfusion was found comparing flaps and controls until the flap's vascular pedicles were divided and ligated, and then flap perfusion fell to zero. Flap and control oxygenation varied significantly only during mobilisation and again, after pedicle division and ligation (F[13,55] = 12.3; P < 0.001)]. This absence of functional ischaemia as a consequence of mobilisation in the model used suggests the practice of delaying electrical conditioning of muscle flaps in dynamic cardiomyoplasty and neoanal sphincteroplasty might be unnecessary if these data are reproduced in human latissimus dorsi muscle. The relevance of these findings to free flap oxygen consumption and to the delay phenomenon is discussed.

show abstract

Improved viability of latissimus dorsi muscle grafts after electrical prestimulation

Cited by 11 publications

References 32 publications

Adaptation of rat jaw muscle fibers in postnatal development with a different food consistency: an immunohistochemical and electromyographic study

Adaptation of rat jaw muscle fibers in postnatal development with a different food consistency: an immunohistochemical and electromyographic study

Cardiac assistance from skeletal muscle: a reappraisal☆

The nutrition of active muscle flaps

Contact Info

Product

Resources

About