Improvement of Chitosan Films Properties by Blending with Cellulose, Honey and Curcumin

Abstract

Chitosan is a natural biopolymer that can be used in biomedical applications, tissue engineering, and wound dressing because of its biodegradability, biocompatibility, and antibacterial activity. The blending of chitosan films with natural biomaterials such as cellulose, honey, and curcumin was studied at different concentrations in order to improve their physical properties. Fourier transform infrared (FTIR) spectroscopy, mechanical tensile properties, X-ray diffraction (XRD), antibacterial effects, and scanning electron microscopy (SEM) were studied for all blended films. The XRD, FTIR, and mechanical results showed that films blended with curcumin were more rigid and compatible and had higher antibacterial effects than other blended films. In addition, XRD and SEM showed that blending chitosan films with curcumin decreases the crystallinity of the chitosan matrix compared to cellulose and honey blending films due to increased intermolecular hydrogen bonding, which reduces the close packing of the CS matrix.

Rotary Friction Welding of Dissimilar Polymer Rods Containing Metal Powder

“…A possible reason is that the distribution of Cu powder or Al powder in the PLA material is uneven or the content of Cu powder or Al powder in the PLA material is too low. Additionally, Cu powder or Al powder has poor compatibility [32,33] with PLA matrix materials, which leads to cracks or peeling of the bending test specimen during the bending test. (c) The average bending strength of the bending test specimen fabricated by RFW is higher than that of the cylinder printed with PLA-containing Cu powder.…”

Effect of Sodium Hydroxide and Tripolyphosphate on Curcumin Release from Chitosan-Based Macroparticles

“…Curcumin (CUR), an orange-yellow hydrophobic polyphenol derived from the rhizomes of the herb Curcuma longa, is another natural bioactive and therapeutic compound due to its anticarcinogenic, antibacterial, antimicrobial, antifungal, antiviral, antimalarial, antioxidant, antimutagenic, cicatrizing, anti-inflammatory, anti-coagulant, anti-fertility, antiprotozal, antifibrotic, antivenom, antiulcer, hypotensive, and anticholesteremic properties, as well as its free-radical effects [3,5,[22][23][24]. Because of its flavoring properties, CUR is used as a food coloring, and as a traditional medicine in India and China for the treatment and prevention of several diseases, such as neurological, oncological, autoimmune, metabolic, cardiovascular, and diabetes, due to its extraordinary activities [3][4][5]23], which have attracted increasing interest from researchers to CUR [25]. However, the use of CUR in therapeutic applications has been limited due to its poor bioavailability and water solubility [4,26,27].…”

“…Chitosan (CS), structurally composed of β-1,4-linked 2-amino-2-deoxy-β-D-glucose and N-acetyl-D-glucosamine units, is a derivate of chitin, the second most abundant polysaccharide in nature after cellulose [1][2][3][4]. Among the various biopolymers, CS has attracted much attention for its remarkable biological and physical properties [4] and exhibits a wide variety of environmentally beneficial properties, such as abundant availability, biodegradability, non-toxicity, biocompatibility, recyclability, physiological inertness, cell adhesion, and stability to air and moisture.…”

“…Among the various biopolymers, CS has attracted much attention for its remarkable biological and physical properties [4] and exhibits a wide variety of environmentally beneficial properties, such as abundant availability, biodegradability, non-toxicity, biocompatibility, recyclability, physiological inertness, cell adhesion, and stability to air and moisture. It also possesses antitumor, mucoadhesive, immunostimulant, antifungal, antimicrobial, antibacterial, antioxidant, hemostatic, and wound healing properties [1][2][3][4], which make it an ideal candidate for pharmaceutical, and industrial applications [1,2,[4][5][6][7][8][9]. In this context, CS can be employed as a recyclable green catalyst [5], in supercapacitors and biopolymer batteries, sensors, and water treatment [2,4].…”

“…In this context, CS can be employed as a recyclable green catalyst [5], in supercapacitors and biopolymer batteries, sensors, and water treatment [2,4]. It also finds wide use in cosmetics, agriculture, food technology as food packaging material, and in the biomedical field, particularly in bioimaging, tissue engineering, wound dressing, and the textile industry, as well as in the design and development of drug delivery systems, implants, contact lenses and protein binding [1][2][3][4][10][11][12][13]. In particular, to design controlled release systems of CS-based drugs, the poor barrier and mechanical properties of CS can be modulated and improved by appropriately acting on the crosslinking process, and/or incorporating materials into CS films [3,6].…”