Steam condensation plays an important role in various engineering processes due to its excellent heat transfer performance. However, condensation in the presence of noncondensable gas has attracted great attention in recent years since noncondensable gas will have a negative effect on condensation heat transfer. The present study proposes a comprehensive model coupled with convective heat transfer, liquid film heat transfer and steam condensation for the heat transfer of condensation with noncondensable gas and uses it in the Program Integrated for Severe Accident Analysis (PISAA) for a nuclear power plant. The condensation heat transfer model has good universality, the calculation process is stable with less iteration and a fast convergence and it is verified and validated by comparing the simulation results of the PISAA and those from traditional containment analysis codes, as well the experiments from the Wisconsin condensation tests; then, a sensitivity analysis for the parameters of the heat transfer coefficient is performed. The validation results show that the average error of the condensation heat transfer coefficient is approximately 10%, and the maximum error does not exceed 30%. The deviation from the experimental data is limited in the acceptable range, which could fulfill the requirement for the analysis of containment accidents in nuclear power plants.