Improving the exploitative and environmental performance of piston engines (PICE) is an urgent task for many engineers and scientists. The article presents the results of the upgrade of a gas-and-air system of a diesel PICE, carried out through changing the turbocharging system’s configuration and modernizing the design of the admittance collector. The authors present a review of studies on the given subject and a description of the object of the research. The study was conducted on the basis of bench tests at a manufacturing plant and mathematical modeling using ACTUS program. The results of experimental studies on the main indicators of a basic and upgraded PICEs are presented. The gas exchange processes in the PICE under examination were studied in detail using mathematical modeling. For the given diesel PICE, improvement of the gas-and-air system leads to a growth in charging efficiency by 2.45-3.92%, a decrease in scavenging factor by 3.11-6.31% and a reduction of specific fuel consumption up to 3.33%. In the conclusion, new directions for increasing the efficiency of the given PICE are offered.