Improvement of Lipid and Terpenoid Yield in Thraustochytrids Using Chemical Regulators: A Review

Chen, Zi-Lei; Yang, Lin-Hui; Tong, Ling-Ling; Wang, Yue; Liu, Meng-Zhen; Guo, Dong-Sheng

doi:10.1007/s12257-023-0086-4

Biotechnol Bioproc E

2023

DOI: 10.1007/s12257-023-0086-4

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Improvement of Lipid and Terpenoid Yield in Thraustochytrids Using Chemical Regulators: A Review

Zi-Lei Chen,

Lin-Hui Yang,

Ling-Ling Tong

et al.

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2024

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Cited by 2 publications

References 116 publications

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Polyketide Synthase Acyltransferase Domain Swapping for Enhanced EPA Recognition and Efficient Coproduction of EPA and DHA in Schizochytrium sp

Zhang,

Wu,

Lin

et al. 2024

J. Agric. Food Chem.

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Polyketide Synthase Acyltransferase Domain Swapping for Enhanced EPA Recognition and Efficient Coproduction of EPA and DHA in Schizochytrium sp

Zhang,

Wu,

Lin

et al. 2024

J. Agric. Food Chem.

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Evaluation of the Protective Role of Vitamin E against ROS-Driven Lipid Oxidation in Model Cell Membranes

Kilicarslan You,

Fuwad,

Lee

et al. 2024

Antioxidants

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Reactive oxygen species (ROS) are chemically reactive oxygen-containing compounds generated by various factors in the body. Antioxidants mitigate the damaging effects of ROS by playing a critical role in regulating redox balance and signaling. In this study, the interplay between reactive oxygen species (ROS) and antioxidants in the context of lipid dynamics were investigated. The interaction between hydrogen peroxide (H2O2) as an ROS and vitamin E (α-tocopherol) as an antioxidant was examined. Model membranes containing both saturated and unsaturated lipids served as experimental platforms to investigate the influence of H2O2 on phospholipid unsaturation and the role of antioxidants in this process. The results demonstrated that H2O2 has a negative effect on membrane stability and disrupts the lipid membrane structure, whereas the presence of antioxidants protects the lipid membrane from the detrimental effects of ROS. The model membranes used here are a useful tool for understanding ROS–antioxidant interactions at the molecular level in vitro.

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Improvement of Lipid and Terpenoid Yield in Thraustochytrids Using Chemical Regulators: A Review

Cited by 2 publications

References 116 publications

Polyketide Synthase Acyltransferase Domain Swapping for Enhanced EPA Recognition and Efficient Coproduction of EPA and DHA in Schizochytrium sp

Polyketide Synthase Acyltransferase Domain Swapping for Enhanced EPA Recognition and Efficient Coproduction of EPA and DHA in Schizochytrium sp

Evaluation of the Protective Role of Vitamin E against ROS-Driven Lipid Oxidation in Model Cell Membranes

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