Improvement of Lipid Profile and Antioxidant of Hyperlipidemic albino Rats by Functional Plantago psyllium Cake

Ismael, Naglaa M.; Shehata, Mohamed G.

doi:10.12944/crnfsj.8.2.08

Cited by 5 publications

(2 citation statements)

References 47 publications

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“…Furthermore, G6 that feed on 12% psyllium seeds was more effective (P≤0.05) in reducing AST, ALT and ALP activities by means 53, 35.3 and 100.85 U/L, respectively but still higher than the values of the negative control group (-) except AST value followed by G5 with means 69.18, 36.6 and 110.35 U/L, respectively but G3 had the lowest effect in reducing liver function by means 86, 45.35 and 125.43 U/L, respectively. The results are in the same line with those of Ismael and Shehata (2020) who showed that plantago psyllium seed is a valuable medicinal plant with plenty of biologically effective compounds. Daily consumption of psyllium seed for 28 days caused significant changes in liver enzymes levels (ALT and AST) in both the control and treatment groups.…”

Section: The Effects Of Feeding With Psyllium Seeds Powder On Tg Tc L...supporting

confidence: 90%

Evaluation Anti-Obesity Activity of Psyllium Seeds Powder on Rats Fed a High Fat Diet

Abdalla

Raya

Ghoniem

et al. 2021

Journal of Food and Dairy Sciences

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Psyllium seeds are a major source of soluble and viscous gel-forming fiber that has been associated with many health benefits such as lowering blood glucose and cholesterol and improving digestive disorders. The study aimed to evaluate the effect of feeding with psyllium seeds powder in obese rats fed on a high-fat. The results indicated that feeding with a high-fat diet caused an increase in the final weight, BWG (%), feed intake, serum glucose, serum lipids, kidney and liver functions as compared negative control group (G1) as result of obesity. On the other hand, feeding with psyllium seeds powder on obese rats fed a high-fat diet significantly reduced in the final weight, BWG, feed intake and FER. Main while, serum glucose was reduced in all treated groups (G3, G4, G5 and G6) as compared with the positive control group. This reduction was ranged from 84.25 mg/dl(G3) to 76.00 mg/dl (G6) furthermore, G6 that fed on 12% psyllium seeds powder whose showed the highest decreased on TC,TG and LDL by means 134,98.25,60.35 mg/dl, respectively and highest increased in HDL by mean 55.25 mg /dl as compared with the positive control group (G2) followed by G5. All treated groups referred to improvement in kidney and liver functions as compared with the positive control group. In conclusion, data of the present study recommended that the daily consumption of psyllium seed obese patient's diets could improve serum glucose and lipid profile and promote weight loss.

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Section: The Effects Of Feeding With Psyllium Seeds Powder On Tg Tc L...supporting

confidence: 90%

Evaluation Anti-Obesity Activity of Psyllium Seeds Powder on Rats Fed a High Fat Diet

Abdalla

Raya

Ghoniem

et al. 2021

Journal of Food and Dairy Sciences

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“…It was reported that the significant increase in HDL-C levels refers to the capability of psyllium seeds to accelerate the decline of radical species created following cholesterol delivery. HDL-c reduces beta-lipoprotein peroxidation by acting as a free radical scavenger (Ismael & Shehata, 2020). Diabetic rats given psyllium husks at a concentration of 5% had the best levels of HDL and LDL cholesterol (Elhassaneen et al, 2021).…”

Section: Resultsmentioning

confidence: 99%

Effect of psyllium seeds and its husk on hypercholesterolemic rats

Rabeh

Refaat

Dhaher

2022

ijhs

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This study was performed to investigate the outcome of psyllium seeds and their husk on lipid profile for 8 weeks of hypercholesterolemic rats. A number of 36 mature male rats were split into two groups. The first six rats in the study were fed a standard diet (served as – ve control group). The second main group (30 rats) was fed on high cholesterol diet to induce hypercholesterolemia for six weeks, then was divided as follows: Subcategories (1) was fed on a diet with high cholesterol (as a positive control group). Subcategories (2 and 3) were on a diet with high cholesterol supplemented with 2.5% and 5% Psyllium husk powder, respectively. Subcategories (4 and 5) were fed on high cholesterol diet supplemented with 2.5 % and 5% Psyllium seed powder, respectively. The results revealed that liver functions were found to be significantly decreased (P<0.05) by Psyllium husk or seeds at the tested levels. Serum kidney functions and lipid profile were appreciably (P<0.05) decreased. At the same time, HDL-C was noticeably increased by psyllium seeds or husk supplementation at the tested levels in comparison to the positive control group.

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Antioxidant and Antimicrobial Activity of Cleome droserifolia (Forssk.) Del. and Its Biological Effects on Redox Status, Immunity, and Gut Microflora

Hashem

Shehata

2021

Animals

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This study aimed to investigate the antioxidant, antimicrobial, and immunomodulatory activities of a Cleome droserifolia (Forssk.) Del. (Cd) shoot methanolic extracts considering the biological activity of its phytogenic compounds. For this purpose, the Cd phenolic compounds were detected, and an in vitro evaluation of the antioxidant and antimicrobial activities of the Cd extract was performed. For a biological evaluation, 30 v-line rabbits were randomly distributed into three groups with treatments including: a basal diet without Cd shoots powder supplement (C group) or supplemented with 1.25- (Cdl group) or 2.5 (Cdh group)-mg Cd/kg dry matter (DM). The Cd extract showed a linear scavenging activity for 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), with the maximal activity observed at a concentration of 1 mg/mL. A total of 16 phenolic compounds were identified by reverse-phase high-performance liquid chromatography (RP-HPLC) in the Cd methanolic extract, among which benzoic acid, rutin, ellagic acid, naringenin, and o-coumaric acid were the major compounds. The methanolic extract of Cd showed inhibitory actions against microbial pathogen species. The in vivo study showed that the two concentrations of Cd significantly improved the redox status of the blood plasma and lysozyme activity. Treatment with Cdh significantly decreased the levels of interleukin-β1 in the blood plasma compared with the control. Moreover, the two concentrations of Cd significantly increased the counts of intestinal and cecal yeast and Lactobacillus species and decreased the Salmonella and Coliform species compared with the control. The aerial parts of the Cd shrub had strong antioxidant, antimicrobial, and immunomodulatory activities, which can improve the overall health status and seem to be related to its impressive range of biologically active phenolic compounds.

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Improvement of Lipid Profile and Antioxidant of Hyperlipidemic albino Rats by Functional Plantago psyllium Cake

Cited by 5 publications

References 47 publications

Evaluation Anti-Obesity Activity of Psyllium Seeds Powder on Rats Fed a High Fat Diet

Evaluation Anti-Obesity Activity of Psyllium Seeds Powder on Rats Fed a High Fat Diet

Effect of psyllium seeds and its husk on hypercholesterolemic rats

Antioxidant and Antimicrobial Activity of Cleome droserifolia (Forssk.) Del. and Its Biological Effects on Redox Status, Immunity, and Gut Microflora

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