Abstract:We investigate that the detection sensitivity in surface plasmon resonance (SPR) biosensors can be significantly enhanced by employing subwavelength dielectric gratings deposited on a gold film. The enhancement is due to an improvement of field-matter interaction, i.e., enhanced evanescent field intensity at the binding region and increased surface reaction area. After a large-area SiO 2 grating fabricated by nanoimprint lithography, the sensor performance measured by parylene film shows that the SPR substrate… Show more
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