Improvement of Sexual Activity, Pregnancy Rate, and Low Plasma Testosterone After Bilateral Varicocelectomy in Impotence and Male Infertility Patients

Younes, Abdel

doi:10.1080/01485010390196706

Cited by 20 publications

(6 citation statements)

References 44 publications

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“…Kim & Choi (1992) detected improvement of the penile blood flow after correction of varicocele on scrotopenograms. Younes (2003) presented that the improvement of sexual activity in impotent patients after receiving bilateral varicocelectomy was 50–75%, including libido, morning erection, duration and percentage of erection, sexual interest and frequency of erection per week. Some limitations of our retrospective study such as the lack of associated data including semen quality and hormone variation are worth noting.…”

Section: Discussionmentioning

confidence: 99%

The relationship between varicoceles and obesity in a young adult population

et al. 2009

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To determine whether a relationship between obesity and varicocele occurrence exists, the prevalence and severity of varicoceles related to obesity were investigated in a general population of young males. A total of 1050 young males attending the Navy Recruit Training Center were evaluated from their physical screening examinations. All subjects underwent history taking and physical examinations to evaluate for the presence and severity of varicocele. The anthropometric indexes including body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) were recorded. All subjects were categorized by quartiles according to each anthropometric index. Means were compared with the Student's t-test. Severity was compared by analysis of variance testing and frequency was analysed using the chi-square method. Statistical significance was considered at p <0.05. A total of 490 (46.67%) subjects had varicoceles. The means of BMI, WC and WHR of those without varicoceles was 23.99 +/- 3.82 kg/m(2), 83.20 +/- 9.97 cm and 0.85 +/- 0.05, respectively. These judged values were greater than those with varicoceles (22.02 +/- 3.18 kg/m(2), 79.19 +/- 9.01 cm and 0.83 +/- 0.05) (p < 0.001). In the univariate regression analysis, BMI, WC and WHR all had a significantly negative correlation with severity of varicocele (all p < 0.001). Analysis comparing varicocele frequency based on each grade per anthropometric index group was performed. The logistic regression revealed that the prevalence of grade II and III varicoceles showed a statistically inverse association with all three anthropometric indexes. The prevalence and severity of varicoceles inversely correlated with obesity. The present data support the explanation that obesity may result in a decreased nutcracker effect, which accounts for prevention of the renal vein compression by the adipose tissue.

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Section: Discussionmentioning

confidence: 99%

The relationship between varicoceles and obesity in a young adult population

et al. 2009

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“…Given the role of testosterone in spermatogenesis, a number of investigators have examined the effects of varicocele and its repair on Leydig cell function and testosterone synthesis. Previous research has linked varicocele to lower testosterone levels [6][7][8][9] and suggests that varicocelectomy may improve testosterone production [10,11]. This review will address more recent studies that attempt to further address these important issues.…”

Section: Introductionmentioning

confidence: 94%

“…Previously, several authors have shown that varicocele repair may result in an improvement in serum testosterone levels in humans [10,11]. Since then, a number of studies have examined the effect of varicocelectomy on serum testosterone, either as a primary aim or in the setting of evaluating other parameters.…”

Section: Varicocelectomy and Testosterone: Human Studiesmentioning

confidence: 99%

The impact of varicocele and varicocele repair on serum testosterone

Tanrikut

McQuaid

Goldstein

2011

Current Opinion in Obstetrics &Amp; Gynecology

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Definitive statements regarding varicocele, varicocelectomy, and testosterone are difficult to make given the frequent absence of control groups and lack of sample group consistency. Despite this, recent well done animal and human studies suggest an adverse effect of varicocele on testosterone and a potential benefit of varicocele repair. Further controlled studies examining testosterone as a primary data point are required.

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“…The progressive negative effect of varicocele on Leydig cell function has been supported by animal studies showing decline in intratesticular testosterone over time in rats with surgically induced varicocele (10). Given the acute surgical onset of the varicocele in animal studies and the relatively short duration of study in animal models compared to human models, it is uncertain how translatable this data is to humans (11,12).…”

Section: Low Serum Testosteronementioning

confidence: 93%