Improvement of the Antioxidative Status of Pig Ovaries by Selenopyran Treatment

Abadjieva, Desislava; Kistanova, Elena; Marchev, Yordan; Nedeva, R.; Vaisberg, C.; Stefanov, R.; Boryaev, G.I.; Nevitov, M.

doi:10.14432/j.macvetrev.2014.08.021

Cited by 2 publications

(2 citation statements)

References 30 publications

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“…The Se content in this organic source was 24%. As mentioned in previous investigations (Abadjieva et al, 2014), the advantages of selenopyran are the lower toxicity in comparison with sodium selenite (LD 50 =1600 mg/kg against LD 50 =3.25 mg/kg) and ability to slowly liberate the selenium according to the needs of the organisms (Boryaev and Kravchenko, 2006).…”

Section: Methodsmentioning

confidence: 93%

The effect of injective application of selenopyran on the prolonged increase of the selenium content in blood and sperm of rams

et al. 2015

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Selenium is a microelement of big importance for male reproduction. As a part of the antioxidative enzyme gluthationperoxidase and structural Se proteins, it plays pivotal role in the defense of spermatozoa against generated ROS and in ensuring of its motility. During the last years the interests to the organic forms of selenium was enhanced because of its better biological utilization. The present work aimed to study the effect of injective application of organic compound selenopyran in rams on the distribution of selenium content in blood and sperm and on the changes in sperm quality. The experiment was conducted with 5 rams from the Synthetic Population Bulgarian Milk breed at the age between 3-7 years and live weight 85-90 kg. The animals were injected once with an oil solution of the selenopyran in dose of 0.1mg/kg live weight (selenium content 24%) 45 days before starting the breeding season. The blood was collected before treatment and 45 days thereafter. At the same time the first and second ejaculates of rams were collected using artificial vagina and analyzed by Sperm Class Analyzer. The selenium content was measured in plasma, blood cells and sperm by atomic absorption spectrometry using SpectrAA 55B double beam spectrometer (Varian, Inc.). The results showed that one injection of organic compound of selenium-selenopyran in dose of 0.1mg/kg live weight ensured the increase and support of high level of selenium in blood (plasma and blood cells) and in sperm during investigated period. That lead to the proper spermatogenesis in 1 The paper presented at the 4th International Congress "New Perspectives and Challenges of Sustainable Livestock Production", Belgrade, Serbia, 7th-9th October, 2015 E. Kistanova et al. 482 testis and allowed the production of qualitative ejaculates with higher number of total spermatozoa as well as of spermatozoa with progressive motility.

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Section: Methodsmentioning

confidence: 93%

The effect of injective application of selenopyran on the prolonged increase of the selenium content in blood and sperm of rams

et al. 2015

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“…The use of injective selenopyran could be advantageous because it has low toxicity (Boryaev and Kravchenko 2006). Selenopyran has been used recently for the improvement of the antioxidant status of pig ovaries (Abadjieva et al 2014). Selenopyran also increased Se content in the sperm of rams (Kistanova et al 2015).…”

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confidence: 99%

Effect of parenteral selenium administration on oxidative status of weaned piglets

et al. 2016

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The aim of the study was to evaluate the effect of additional selenium injection after weaning on the selenium (Se) status of piglets and to find whether the selected dose would be appropriate with respect to the level of oxidative stress. Another goal was to compare the efficacy and safety of sodium selenite and selenopyran as selenium sources for parenteral administration to piglets. Altogether 30 piglets were divided equally into three groups. Piglets in group 1 were injected i.m. with sodium selenite, piglets in group 2 were injected with selenopyran. The dose was 0.42 mg Se/kg body weight for both groups. Piglets in group 3 were given only saline. As expected, the study revealed low Se serum concentrations in weaned piglets. The injection of sodium selenite increased Se serum concentrations but did not have a positive effect on the peroxidase activities. Administration of selenopyran did not influence Se concentrations and gluthation peroxidase activities. The selected dose did not have a significant impact on the level of the oxidative stress. The piglets receiving Se only from the feed achieved comparable gluthation peroxidase activities during the trial. It seems that despite initially low Se concentrations, the physiological requirements for gluthation peroxidase synthesis were met with the feed consumption as the only Se source. The results of the study are important because until now it was unclear whether the selected dose would have negative effects on the organism with respect to the induction of oxidative stress in piglets.

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Improvement of the Antioxidative Status of Pig Ovaries by Selenopyran Treatment

Cited by 2 publications

References 30 publications

The effect of injective application of selenopyran on the prolonged increase of the selenium content in blood and sperm of rams

The effect of injective application of selenopyran on the prolonged increase of the selenium content in blood and sperm of rams

Effect of parenteral selenium administration on oxidative status of weaned piglets

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