Improvements in cardiovascular risk profile after large-volume lipoplasty: A 1-year follow-up study

Giese, Sharon Y.; Neborsky, Rebecca; Bulan, Erwin J.; Spear, Scott L.; Yanovski, Jack A.

doi:10.1067/maj.2001.120434

Cited by 17 publications

(13 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Others have shown a sustained weight reduction of 3 kg (18) in obese women at 6‐months following large‐volume lipectomy (>5,000 ml), and 4.6 kg (19) following small‐volume lipectomy at 6‐months, but the weight maintenance was by design. In another study, weight reduction after large‐volume liposuction remained at 4 months (20), and 1 year (21). However, patients underwent a larger volume of AT removal with or without ancillary procedures (abdominoplasty/body lift), the weight of skin removal was not reported, and again there was no control group.…”

Section: Discussionmentioning

confidence: 98%

Fat Redistribution Following Suction Lipectomy: Defense of Body Fat and Patterns of Restoration

Hernandez

Kittelson

Law

et al. 2011

Obesity

View full text Add to dashboard Cite

No randomized studies in humans have examined whether fat returns after removal or where it returns. We undertook a prospective, randomized‐controlled trial of suction lipectomy in nonobese women to determine if adipose tissue (AT) is defended and if so, the anatomic pattern of redistribution. Healthy women with disproportionate AT depots (lower abdomen, hips, or thighs) were enrolled. Baseline body composition measurements included dual‐energy X‐ray absorptiometry (DXA) (a priori primary outcome), abdominal/limb circumferences, subcutaneous skinfold thickness, and magnetic resonance imaging (MRI) (torso/thighs). Participants (n = 32; 36 ± 1 year) were randomized to small‐volume liposuction (n = 14, mean BMI: 24 ± 2 kg/m2) or control (n=18, mean BMI: 25 ± 2) following baseline. Surgery group participants underwent liposuction within 2–4 weeks. Identical measurements were repeated at 6 weeks, 6 months, and 1 year later. Participants agreed not to make lifestyle changes while enrolled. Between‐group differences were adjusted for baseline level of the outcome variable. After 6 weeks, percent body fat (%BF) by DXA was decreased by 2.1% in the lipectomy group and by 0.28% in the control group (adjusted difference (AD): −1.82%; 95% confidence interval (CI): −2.79% to −0.85%; P = 0.0002). This difference was smaller at 6 months, and by 1 year was no longer significant (0.59% (control) vs. −0.41% (lipectomy); AD: −1.00%; CI: −2.65 to 0.64; P = 0.23). AT reaccumulated differently across various sites. After 1 year the thigh region remained reduced (0.77% (control) vs. −1.83% (lipectomy); AD: −2.59%; CI: −3.91 to −1.28; P = 0.0001), but AT reaccumulated in the abdominal region (0.64% (control) vs. 0.42% (lipectomy); AD: −0.22; CI: −2.35 to 1.91; P = 0.84). Following suction lipectomy, BF was restored and redistributed from the thigh to the abdomen.

show abstract

Section: Discussionmentioning

confidence: 98%

Fat Redistribution Following Suction Lipectomy: Defense of Body Fat and Patterns of Restoration

Hernandez

Kittelson

Law

et al. 2011

Obesity

View full text Add to dashboard Cite

show abstract

“…Giese et al [4,5] demonstrated a reduction in weight, body mass index (BMI), fasting insulin levels, and blood pressure in large-volume liposuction patients during a 1-year and 4-month study. Klein et al [6] presented a study of large-volume abdominal liposuction with 15 patients.…”

Section: Introductionmentioning

confidence: 98%

Large-Volume Liposuction and Prevention of Type 2 Diabetes: A Preliminary Report

Narsete¹,

Narsete²,

Buckspan³

et al. 2011

Aesth Plast Surg

View full text Add to dashboard Cite

This report presents a preliminary study investigating the effects of large-volume liposuction on the parameters that determine type 2 diabetes. The study enrolled 31 patients with a body mass index (BMI) exceeding 30 kg/m(2) over a 1-year period. All the liposuction procedures were performed with the patient under local anesthesia using ketamine/valium sedation. Pre- and postoperative blood pressure, fasting glucose, glycosylated hemoglobin (HbA1C), weight, and BMI were evaluated for 16 of the 30 patients who returned for a follow-up visit 3 to 12 months postoperatively. The average aspirate was 8,455 ml without dermolipectomy and 5,795 ml with dermolipectomy. The data reveal a trend of improvement in blood sugar levels associated with weight loss that helps the patients. The average blood sugar level dropped 18% in our return patients, and the average weight loss was 9.2%. The average drop in BMI was 6.2%, and HbA1C showed a decrease of 2.3%. The patients with the best weight loss had the best reduction in blood sugar level and blood pressure. No transfers to the hospital and no thromboebolism occurred for any of the 31 patients. One dehiscence, two wound infections, and three seromas were reported. The authors hypothesize that large-volume liposuction in their series may have motivated some to diet, which could be explored in a larger series with control groups. Liposuction alone did not improve obesity but helped to motivate some of the patients to lose weight. These patients had the best results.

show abstract

“…The superb work by Sharon Giesse and others has clearly shown that large liposuction can alter the postoperative metabolism in most patients [3,4]. Had the authors simply assessed the hemoglobin A1c level preoperatively in 296 patients, then again after 3 or 4 months, they could have answered the question once and for all.…”

mentioning

confidence: 99%

“…Everyone knows that obesity is associated with an altered metabolism, which includes type 2 diabetes. Whether the hypoglycemia occurs as a result of insufficient or partially ineffective insulin, an immune response to insulin, or hyperactive adipose tissue that soaks up the available insulin, the reduction of fat, by gastric bypass [1][2][3][4], serious dieting, or liposuction, reduces insulin needs substantially.…”

mentioning

confidence: 99%

Safe Total Corporal Contouring with Large-Volume Liposuction for the Obese Patient

Ersek

2007

Aesth Plast Surg

View full text Add to dashboard Cite

Improvements in cardiovascular risk profile after large-volume lipoplasty: A 1-year follow-up study

Abstract: Should these results be confirmed in larger studies, lipoplasty may prove to be a valuable tool for reducing some of the co-morbid conditions associated with obesity. (Aesthetic Surg J 2001;21:527-531.).

Cited by 17 publications

References 21 publications

Fat Redistribution Following Suction Lipectomy: Defense of Body Fat and Patterns of Restoration

Fat Redistribution Following Suction Lipectomy: Defense of Body Fat and Patterns of Restoration

Large-Volume Liposuction and Prevention of Type 2 Diabetes: A Preliminary Report

Safe Total Corporal Contouring with Large-Volume Liposuction for the Obese Patient

Contact Info

Product

Resources

About