Improvements of diagnostic accuracy and visualization of vertebral metastasis using multi-level virtual non-calcium reconstructions from dual-layer spectral detector computed tomography

Abdullayev, Nuran; Hokamp, Nils Große; Lennartz, Simon; Holz, Jasmin A.; Romman, Z; Pahn, Gregor; Neuhaus, Victor; Maintz, David; Krug, Barbara; Borggrefe, Jan

doi:10.1007/s00330-019-06233-5

Cited by 41 publications

(48 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Abdullayev et al (19) evaluated the diagnostic accuracy and visualization of vertebral metastasis using virtual noncalcium reconstructions. They used a prototype image recomposition algorithm that allows for the reconstruction of virtual non-calcium images based on spectral base images (SBI).…”

Section: Virtual Non-calcium Reconstruction For Diagnosing Vertebral Metastasismentioning

confidence: 99%

Application of Dual-Energy Spectral Computed Tomography to Thoracic Oncology Imaging

Kim

Park

et al. 2020

Korean J Radiol

View full text Add to dashboard Cite

Computed tomography (CT) is an important imaging modality in evaluating thoracic malignancies. The clinical utility of dual-energy spectral computed tomography (DESCT) has recently been realized. DESCT allows for virtual monoenergetic or monochromatic imaging, virtual non-contrast or unenhanced imaging, iodine concentration measurement, and effective atomic number (Zeff map). The application of information gained using this technique in the field of thoracic oncology is important, and therefore many studies have been conducted to explore the use of DESCT in the evaluation and management of thoracic malignancies. Here we summarize and review recent DESCT studies on clinical applications related to thoracic oncology.

show abstract

Section: Virtual Non-calcium Reconstruction For Diagnosing Vertebral Metastasismentioning

confidence: 99%

Application of Dual-Energy Spectral Computed Tomography to Thoracic Oncology Imaging

Kim

Park

et al. 2020

Korean J Radiol

View full text Add to dashboard Cite

show abstract

“…Similarly, receiver operating characteristic curve analysis of bone marrow attenuation on VNCa datasets has also demonstrated excellent sensitivity, specificity, and accuracy, ranging 85–96%, 82–90%, and 85–91%, respectively, using cutoff values from -80 and -12 HU [ 46 , 56 – 58 ].…”

Section: Vnca Clinical Applicationsmentioning

confidence: 98%

“…Moreover, its rapid acquisition time lends it favorably to emergency settings [46]. Several studies have been carried out to evaluate the diagnostic performance of VNCa reconstructions to detect acute vertebral fractures [56][57][58]. BME detection has been qualitatively assessed by using color-coded images and quantitatively using region-of-interest-based measurements of bone marrow attenuation.…”

Section: Spine Fracturesmentioning

confidence: 99%

See 1 more Smart Citation

Virtual non-calcium dual-energy CT: clinical applications

et al. 2021

View full text Add to dashboard Cite

Dual-energy CT (DECT) has emerged into clinical routine as an imaging technique with unique postprocessing utilities that improve the evaluation of different body areas. The virtual non-calcium (VNCa) reconstruction algorithm has shown beneficial effects on the depiction of bone marrow pathologies such as bone marrow edema. Its main advantage is the ability to substantially increase the image contrast of structures that are usually covered with calcium mineral, such as calcified vessels or bone marrow, and to depict a large number of traumatic, inflammatory, infiltrative, and degenerative disorders affecting either the spine or the appendicular skeleton. Therefore, VNCa imaging represents another step forward for DECT to image conditions and disorders that usually require the use of more expensive and time-consuming techniques such as magnetic resonance imaging, positron emission tomography/CT, or bone scintigraphy. The aim of this review article is to explain the technical background of VNCa imaging, showcase its applicability in the different body regions, and provide an updated outlook on the clinical impact of this technique, which goes beyond the sole improvement in image quality.

show abstract

“…Computed tomography is particularly useful for further characterization of tumors with mineralized matrix and of sclerotic tumors. Most recently the application of dual energy CT virtual non-calcium algorithms has proven to be a valuable tool in the assessment of MBD lesions and disease load [33][34][35] as well as in identifying focal biopsy targets [36]. Moreover, CT is also useful for further characterization of tumors in the cortex, paracortical, and periosteal locations.…”

Section: Cross-sectional Imaging: Mri and Ctmentioning

confidence: 99%

State-of-the-art imaging for diagnosis of metastatic bone disease

Isaac

Dalili

et al. 2020

Radiologe

View full text Add to dashboard Cite

Table 1 Epidemiological indicators: total number of cancer cases in Germany in 2013 (modified according to [21]) New cases Women Men Death Women Men Absolute number 229,920 252,550 Absolute number 101,779 121,314 Mean age at diagnosis 67.2 68.3 Mean age at diagnosis 74.3 73.3 Raw rate 558.4 639.9 Raw rate 247.2 307.7 Age-standardized rate a 351.2 434.1 Age-standardized rate a 126.7 196.5 Current trend +0.8%-0.5% Current trend-0.7%-1.2% Age-standardized rate a 327.9 447.6 Age-standardized rate a 126.8 211.8 Prognosis for 2020 (absolute number) 244,100 274,900 Prognosis for 2020 (absolute number)-0.8%-1.5%

show abstract

Improvements of diagnostic accuracy and visualization of vertebral metastasis using multi-level virtual non-calcium reconstructions from dual-layer spectral detector computed tomography

Cited by 41 publications

References 36 publications

Application of Dual-Energy Spectral Computed Tomography to Thoracic Oncology Imaging

Application of Dual-Energy Spectral Computed Tomography to Thoracic Oncology Imaging

Virtual non-calcium dual-energy CT: clinical applications

State-of-the-art imaging for diagnosis of metastatic bone disease

Contact Info

Product

Resources

About