Improving Adverse Drug Reaction Monitoring

Prescription‐event and other forms of epidemiological monitoring of side‐effects in the UK

“…Methods of improving ADR monitoring have been discussed by a number of people; [14 –17]. Of these, one of the most interesting, as reporting from hospitals is so important, is the eight‐fold improvement in reporting rates noted by Winstanley and colleagues [17] who devised a pharmacy‐based reporting scheme at the Royal Liverpool Hospital and the University of Liverpool.…”

Benzodiazepine drugs in Australia: associated mortality and morbidity

“…Correspondence and requests for reprints to A. Lockwood, Addiction Studies Unit, Curtin University of Technology, GPO Box UI987, Perth, WA 6ooi, Australia. effects to drugs from reports mainly submitted by medical practitioners, pharmacists and pharmaceutical companies (Table i) [4,5]-…”

“…[5]-Mortality and morbidity figures are not standardized in relation to the amount of each drug prescribed nor in relation to patient exposure.…”

La notificación de los efectos adversos de los medicamentos

“…En este sentido, un estudio realizado en la década de los ochenta ya indicaba que una gran proporción de las que los expertos consideraban como las reacciones adversas de mayor trascendencia identificadas entre los años sesenta y ochenta, no fueron detectadas inicialmente mediante notificación voluntaria (3,4). Mientras que por otro lado, no es infrecuente que se comuniquen sospechas que realmente no son reacciones adversas pero que pueden dar lugar a una gran controversia, e incluso llevar a la retirada del mercado del medicamento sospechoso aunque realmente no produzca el problema (5,6).…”