Improving Blood Flow Simulations by Incorporating Measured Subject-Specific Wall Motion

Lantz, Jonas; Dyverfeldt, Petter; Ebbers, Tino

doi:10.1007/s13239-014-0187-5

Cited by 22 publications

(19 citation statements)

References 19 publications

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“…The Swedish National Infrastructure for Computing (SNIC) is acknowledged for computational resources provided by the National Supercomputer Centre (Grant No. SNIC2014- [11][12][13][14][15][16][17][18][19][20][21][22].…”

Section: Acknowledgmentsmentioning

confidence: 99%

Comparison of respiratory motion suppression techniques for 4D flow MRI

Dyverfeldt

Ebbers

2017

Magnetic Resonance in Med

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PurposeThe purpose of this work was to assess the impact of respiratory motion and to compare methods for suppression of respiratory motion artifacts in 4D Flow MRI.MethodsA numerical 3D aorta phantom was designed based on an aorta velocity field obtained by computational fluid mechanics. Motion‐distorted 4D Flow MRI measurements were simulated and several different motion‐suppression techniques were evaluated: Gating with fixed acceptance window size, gating with different window sizes in inner and outer k‐space, and k‐space reordering. Additionally, different spatial resolutions were simulated.ResultsRespiratory motion reduced the image quality. All motion‐suppression techniques improved the data quality. Flow rate errors of up to 30% without gating could be reduced to less than 2.5% with the most successful motion suppression methods. Weighted gating and gating combined with k‐space reordering were advantageous compared with conventional fixed‐window gating. Spatial resolutions finer than the amount of accepted motion did not lead to improved results.ConclusionRespiratory motion affects 4D Flow MRI data. Several different motion suppression techniques exist that are capable of reducing the errors associated with respiratory motion. Spatial resolutions finer than the degree of accepted respiratory motion do not result in improved data quality. Magn Reson Med 78:1877–1882, 2017. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution Non‐Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Section: Acknowledgmentsmentioning

confidence: 99%

Comparison of respiratory motion suppression techniques for 4D flow MRI

Dyverfeldt

Ebbers

2017

Magnetic Resonance in Med

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“…Also included are the mass wave reflections from the arterial branches, the pulsatile movement of the heart, the residual stress, and the grade of fixation of the wall. 5 , 6 Finally, the knowledge of the embryologic origin of the anatomical variations of the aortic arch is a very important issue in order to understand the pathophysiology of the aortic dissection. 7 – 10 .…”

Section: Introductionmentioning

confidence: 99%

Incidence of Branching Patterns Variations of the Arch in Aortic Dissection in Chinese Patients

Tapia

Zhu

et al. 2015

Medicine

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Several authors have described anatomic variations of the aortic arch in 13% to 20% of the patients who do not have aortic disease. However, few studies have evaluated these patterns in the thoracic aortic dissection (TAD). In the authors’ knowledge, this is the first survey that specifically investigates the frequency of these variations in a broad, nonselected group of Chinese patients with aortic dissection. Furthermore, it compares this group with a group of patients without aortic disease.The objective of this study was to define the variation frequency of the aortic arch branches pattern using the tomographic studies of 525 Chinese patients with a diagnosis of TAD. The Stanford classification was used to set the site of the initial tear of the dissection. In addition, we performed an epidemiological analysis of the aortic arch anatomic variations in TAD, and its possible implications for surgical or endovascular treatment. The general hypothesis proposal asserted that Chinese patients with dissection of the aorta have a similar incidence of variations of the aortic arch to the patients without aortic disease.A retrospective study of cases and controls was carried out using the tomographic studies (CT) of all patients admitted to the First Affiliated Hospital of Zhengzhou University, located at Henan-China, with a confirmed diagnosis of aortic dissection from January 2012 until December 2014. The group of cases consisted of 525 patients: 374 men and 151 women, with a mean age of 52.27 years (range, 20–89). The average age of the patients with Stanford A and B aortic dissection was 49.46 and 53.67, respectively. The control group consisted of 525 unselected patients without TAD who underwent a CT scan of the chest due to other indications. This group consisted of 286 men and 239 women, with a mean age of 53.60 years (range, 18–89). All the patients with aneurysm or dissection were excluded from the control group. We performed a statistical analysis of demographic data.The study found 7 different patterns of the aortic arch on both groups of cases and controls. Within the 525 patients with TAD were observed 85 (16.19%) anatomical variations, while the control group showed 112 variations (21.33%); P = 0.033. The most common anatomical variant was the bovine arch, found in 62 (11.80%) cases of TAD compared with 77 (14.66%) in the control group; P = 0.172. Anatomical variations were observed in 14.32% of the patients with Stanford A dissection and 17.09% of the patients with Stanford B dissection; P = 0.425. Patients with Stanford A dissection showed the pattern of bovine arch in 23 (13.21%) of 174 cases. In contrast, the patients with Stanford B dissection showed it in 39 (11.11%) of 351 cases; P = 0.481. The anatomical variant defined as vertebral artery of direct origin of the aortic arch was more frequent in the patients with Stanford B dissection (5.12%). The patients with Stanford A dissection presented this pattern in 1.14% of the cases; P = 0.025. This study observed an increased frequency of aort...

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“…Studies in healthy aortae have shown that inclusion of the motion of the vessel wall alters the WSS values (Lantz et al, 2014;Reymond et al, 2013). However, it is not clear how much WSS will be affected by the wall motion in simulations of AD, wherein vessel wall distensibility is reduced (Ganten et al, 2009).…”

Section: Resultsmentioning

confidence: 99%