Assessment of management commitments is required for investment in Occupational health and safety program. This systemic literature review evaluates 15 cases of Occupational health and safety (OHS) interventions to assess whether the implementation of OHS is beneficial. Search engines used in literature review are Medline, Embase, Web of Science, Cochrane Library, Pubmed. Studies related to benefit cost analysis included in the search include also looking at company productivity. The focus of this analysis includes samples, design, theoretical framework, implementation OHS, validity and results.Results show,in 15 cases, cross-sectional research design looked at pre-after comparisons in the absence of control groups. The positive return on investment from the implementation of OHS is shown in 13 studies. Two other studies concluded that their chosen implementation of OHSwas not cost-effective. The main benefit is to reduce sick leave. In 3 cases the perceived benefit is an increase in productivity and quality. The conclusions in this study required a guideline for the evaluation of the implementation of OHS.