Land use and land cover (LULC) change is one of the primary contributors to hydrological change in urban watersheds and can potentially influence stream flow and flood volume. Understanding the impacts of LULC change on urban hydrological processes is critical to effective urban water management and minimizing flood risks. In this context, this study aims to determine the impacts of LULC change on hydrological response in a fast transitioning watershed for the predicted years of 2050 and 2080. This research employs the hybrid land use classification technique, Cellular Automata–Markov (CA–Markov) model to predict land use changes, utilizing land use data from 2001, 2013, and 2021. Additionally, it incorporates a calibrated, event-specific hydrologic model known as the Personal Computer Storm Water Management Model (PCSWMM) to assess alterations in hydrological responses for storm events of various magnitudes. The findings indicate a transition of the watershed into an urbanized landscape, replacing the previous dominance of agriculture and forested areas. The initial urban area, constituting 11.6% of the total area in 2021, expands to cover 34.1% and 44.2% of the total area by 2050 and 2080, respectively. Due to the LULC changes, there are increases in peak discharge of 5% and 6.8% and in runoff volume of 8% and 13.3% for the years 2050 and 2080 for a 100-year return period storm event. Yet, the extent of these changes intensifies notably during storm events with lower return periods. This heightened impact is directly attributed to the swift urbanization of the watershed. These results underscore the pressing necessity to regulate LULC change to preserve the hydrological equilibrium.