Improving DOI Information Using 3-layer Crystals for Small Animal PETs

Hong, S. J.; Lee, Jun S.; Sim, K. S.; Kim, S.M.; Moon, D. H.; Hong, Bing; Lee, K.S.; Park, J.W.; Park, S.; Lee, M.C.; Choe, J.G.; Rhee, J.T.

doi:10.1109/nssmic.2004.1462748

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…We undertook to combine these two approaches to construct a 3-layer small animal PET scanner, so as to improve spatial resolution and DOI without sacrificing sensitivity [11], [12]. In this paper, we present the recent progress made toward the development of the 3-layer PET scanner using LGSO crystals [13] and Hamamatsu H9500 PMTs.…”

Section: Introductionmentioning

confidence: 99%

Verification of concepts for DOI determination in a three-layer small animal PET

Kwon

Lee

Ito

et al. 2007

2007 IEEE Nuclear Science Symposium Conference Record

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Improved spatial resolution without sacrificing sensitivity is one of the most challenging development goals for small animal PET scanners. The 3-layer configuration that we proposed utilizes relative offsets of half a crystal pitch in x-and y-directions, and pulse shape discrimination to obtain depth of interaction (DOI). Three layers of crystals with a dimension 1.5 1.5 7.0 mm 3 were composed of a L 0.2 GSO (Lu 0.4 Gd 1.6 SiO 4 : Ce) crystal layer and a L 0.9 GSO (Lu 1.6 Gd 0.4 SiO 4 ) crystal layer aligned with each other, and a L 0.9 GSO crystal layer offset of at half a crystal pitch in x-and y-directions. The L 0.2 GSO crystal layer was attached to a Hamamatsu H9500 flat-panel PMT. The devised small animal PET scanner has a diameter of 84 mm with one detector ring, and can be upgraded to two detector rings. GEANT4 Monte-Carlo simulation was used to estimate sensitivities of ~12 % and ~20%, respectively, at the center of one and two PMT ring system. We present flood images with peak-to-valley ratios of about 5~6 obtained using 22 Na and layer identification capability of ~95% with pulse shape analysis using a 100 mega-sample per second (MSPS) Analog-to-Digital Converter (ADC), and verified the basic concepts of the multi-layer small animal PET. Index Terms-Depth of Interaction (DOI), Cerium Doped lutetium Gadolinium Oxyorthosilicate (LGSO), Three-layer Crystal, Animal PET

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Section: Introductionmentioning

confidence: 99%

Verification of concepts for DOI determination in a three-layer small animal PET

Kwon

Lee

Ito

et al. 2007

2007 IEEE Nuclear Science Symposium Conference Record

View full text Add to dashboard Cite

show abstract

“…We undertook to combine these two approaches and to construct a 3-layer small animal PET scanner, so as to improve spatial resolution and DOI without sacrificing sensitivity [12], [13]. In this paper, we present the recent progress made toward the development of the 3-layer PET scanner using LGSO crystals (Hitachi Chemical Co., Ltd., Ibaraki, Japan) [14] and Hamamatsu H9500 PMTs.…”

mentioning

confidence: 99%

Concept Verification of Three-Layer DOI Detectors for Small Animal PET

Hong¹,

Kwon

Ito

et al. 2008

IEEE Trans. Nucl. Sci.

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Improved spatial resolution without sacrificing sensitivity is one of the most challenging developmental goals for small animal PET scanners. The 3-layer configuration that we propose here utilizes relative offsets of half a crystal pitch in xand y-directions, and pulse shape discrimination to obtain depth of interaction (DOI). Three layers of crystals with a dimension 1.5 1.5 7.0 mm 3 were composed of a L 0 2 GSO (Lu 0 4 Gd 1 6 SiO 4 : Ce) crystal layer and a L 0 9 GSO (Lu 1 8 Gd 0 2 SiO 4 : Ce) crystal layer aligned with each other, and a L 0 9 GSO crystal layer offset at half a crystal pitch in x-and y-directions. The L 0 9 GSO crystal layer was attached to a Hamamatsu H9500 flat-panel PMT. The devised small animal PET scanner has a diameter of 84 mm with one detector ring, and can be upgraded to two detector rings. GEANT4 Monte-Carlo simulation was used to estimate sensitivities of 12% and 20%, respectively, at the center of one and two PMT ring system with an energy window of 350 750 keV. We present flood images with peak-to-valley ratios of about 5-6 obtained using 22 Na and layer identification capability of 99% with pulse shape analysis, and verified the basic concepts of multi-layer small animal PET.Index Terms-Animal PET, depth of interaction (DOI), lutetium gadolinium oxyorthosilicate (LGSO), three-layer crystal.

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Improving DOI Information Using 3-layer Crystals for Small Animal PETs

Cited by 2 publications

References 6 publications

Verification of concepts for DOI determination in a three-layer small animal PET

Verification of concepts for DOI determination in a three-layer small animal PET

Concept Verification of Three-Layer DOI Detectors for Small Animal PET

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