Improving Effective Lens Position Prediction for Transscleral Fixation of Intraocular Lens Among Congenital Ectopia Lentis Patients

Zou, Minjie; Lian, Zhangkai; Young, Charlotte Aimee; Liu, Siyuan; Zhang, Xinyu; Zheng, Danying; Jin, Guangming

doi:10.1016/j.ajo.2023.03.021

American Journal of Ophthalmology

2023

DOI: 10.1016/j.ajo.2023.03.021

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Improving Effective Lens Position Prediction for Transscleral Fixation of Intraocular Lens Among Congenital Ectopia Lentis Patients

Minjie Zou¹,

Zhangkai Lian²,

Charlotte Aimee Young³

et al.

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2024

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Influencing factors of effective lens position in patients with Marfan syndrome and ectopia lentis

Shen,

Chen,

Jia

et al. 2024

Br J Ophthalmol

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AimsThe aim of this study was to analyse the effective lens position (ELP) in patients with Marfan syndrome (MFS) and ectopia lentis (EL).MethodsPatients with MFS undergoing lens removal and primary intraocular lens (IOL) implantation were enrolled in the study. The back-calculated ELP was obtained with the vergence formula and compared with the theoretical ELPs. The back-calculated ELP and ELP error were evaluated among demographic and biometric parameters, including axial length (AL), corneal curvature radius (CCR) and white-to-white (WTW).ResultsA total of 292 eyes from 200 patients were included. The back-calculated ELP was lower in patients undergoing scleral-fixated IOL than those receiving in-the-bag IOL implantation (4.54 (IQR 3.65–5.20) mm vs 4.98 (IQR 4.56–5.67) mm, p<0.001). The theoretical ELP of the SRK/T formula exhibited the highest accuracy, with no difference from the back-calculated ELP in patients undergoing in-the-bag IOL implantation (5.11 (IQR 4.83–5.65) mm vs 4.98 (IQR 4.56–5.67) mm, p=0.209). The ELP errors demonstrated significant correlations with refraction prediction error (PE): a 1 mm ELP error led to PE of 2.42D (AL<22 mm), 1.47D (22 mm≤AL<26 mm) and 0.54D (AL≥26 mm). Multivariate analysis revealed significant correlations of ELP with AL (b=0.43, p<0.001), CCR (b=−0.85, p<0.001) and WTW (b=0.41, p=0.004).ConclusionThis study provides novel insights into the origin of PE in patients with MFS and EL and potentially refines existing formulas.

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Influencing factors of effective lens position in patients with Marfan syndrome and ectopia lentis

Shen,

Chen,

Jia

et al. 2024

Br J Ophthalmol

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show abstract

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Improving Effective Lens Position Prediction for Transscleral Fixation of Intraocular Lens Among Congenital Ectopia Lentis Patients

Cited by 1 publication

References 48 publications

Influencing factors of effective lens position in patients with Marfan syndrome and ectopia lentis

Influencing factors of effective lens position in patients with Marfan syndrome and ectopia lentis

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