2023
DOI: 10.1021/acs.langmuir.3c00842
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Improving Hydrophobicity of Collagen with Silica Nanoparticles: Probing a Noncovalent Approach

Koilraj Stephen,
Varnakumar Gayathri,
Nitin Prakash Lobo
et al.

Abstract: Collagen-based materials have a wide range of applications in wound care, tendon repair, cartilage repair, etc. Improving certain properties such as hydrophobicity can diversify the application areas. In this work, we investigated the noncovalent interactions of suitably functionalized silica nanoparticles with collagen for the possibility of improving hydrophobicity. Functionalization on silica nanoparticles was achieved via Cu(I)catalyzed azide−alkyne cycloaddition (CuAAC) or "click" reaction using surface g… Show more

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