Improving medication safety in oncology care: impact of clinical pharmacy interventions on optimizing patient safety

Patel, Himanshu; Parthasarathi, G

doi:10.1007/s11096-019-00860-0

Cited by 15 publications

(11 citation statements)

References 26 publications

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“…Patel et al. investigated adverse drug reactions to antineoplastic agents and the impact of clinical pharmacists in minimizing reactions, 18 which we did not assess directly. In a prospective study in France in which 489 adult cancer patients were admitted to a hematology/oncology department over one year, the pharmacists identified 552 drug-related problems which accounted for 12.6% of reviewed prescription.…”

Section: Discussionmentioning

confidence: 99%

“…Although several studies have evaluated the impact of pharmacists in general, the role of clinical pharmacists in oncology has been evaluated in a few studies. 16–19 Most of these studies evaluated their roles in the outpatient settings, 17,19–22 and only a few were conducted among inpatients. 16,18,23,24 Therefore, we evaluated the impact of clinical pharmacists’ interventions (CPIs) in patients admitted to the medical oncology service at a comprehensive cancer center.…”

Section: Introductionmentioning

confidence: 99%

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Impact of clinical pharmacists in an inpatient medical oncology service: A prospective study at a comprehensive cancer center in Jordan

Faqeer

Mustafa

Al-Jalil

et al. 2020

J Oncol Pharm Pract

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Introduction Clinical pharmacy is considered an integral discipline in the health care system for optimizing therapy and reducing drug-related problems. The objective of this study was to evaluate the impact of clinical pharmacists in optimizing management in a medical oncology service. Methods A prospective study was conducted at King Hussein Cancer Center between July 2019 and September 2019 of patients admitted to the medical oncology service. The impact of clinical pharmacists was measured by evaluating their interventions, defined as actions that were expected to result in a change in patient management. Data were collected daily by routine review of patients' profiles and by recording clinical pharmacists’ interventions. The data collected were baseline characteristics of patients, numbers and types of clinical pharmacists’ interventions, their significance, medications involved, and rate of acceptance of clinical pharmacists’ interventions by physicians. The significance of each intervention was assessed by two clinical pharmacists on a Hatoum scale. Physicians’ acceptance was assessed by whether the recommendations were implemented. Results During the study period, 748 patients were included, of whom 605 required a total of 1683 clinical interventions. The mean age was 56.3 years (±15.5 SD). Of the interventions, 39% resulted in initiation of a drug and 25% in drug discontinuations. The drug group most commonly associated with clinical pharmacists’ interventions was antibiotics (26.5%). Physicians accepted 98% of the clinical pharmacists’ interventions, and 92.4% of the interventions brought care to a more appropriate level and were considered significant. Conclusion Most patients in the medical oncology service required clinical pharmacists’ interventions, as demonstrated by the high number of significant clinical pharmacists’ interventions. Studies should be conducted to follow up these findings with respect to patient outcomes and cost savings.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of clinical pharmacists in an inpatient medical oncology service: A prospective study at a comprehensive cancer center in Jordan

Faqeer

Mustafa

Al-Jalil

et al. 2020

J Oncol Pharm Pract

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“…The effect size of PIs as impact criteria on clinical parameters, health problems, cost reduction and increase in profits is a measure of the direct impact the pharmacist had on patient health and quality of care system [ 68 , 69 , 75 , 175 , 231 , 232 ]. However, non-pharmacological treatment, care received from other health professionals, the placebo effect and remission of disease can all contribute to the results.…”

Section: Discussionmentioning

confidence: 99%

Comprehensive Medication Management Services with a Holistic Point of View, a Scoping Review

2023

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Implementing Comprehensive Medication Management (CMM) services uncovered the importance of the totality of the patient’s perspective in this process. The holistic approach takes into account the physical, mental and emotional well-being of individuals, as well as their socioeconomic circumstances. The aim of this study was to characterize the scientific evidence associated with CMM services that included this holistic approach. A scoping review was conducted based on Arksey and O’Malley’s method. Searches were performed in Google Scholar for papers published between 2010 and 2020 in English, Spanish and Portuguese. Study design, health contexts, sample of patients, results obtained, barriers and facilitators, and the integration of a holistic approach were determined. Two hundred and eighteen papers were evaluated, most of which focused on the implementation of this service through prospective observational studies. A minority of studies reported on a holistic approach, a smaller number examined the effect of social determinants of health, the patient’s medication experiences and the pharmacotherapy outcomes from the patient’s perspective. Despite the progress achieved, most of the referents do not yet reflect a broader view of the patient’s life situation and its relationship to pharmacotherapy and the ways in which the pharmacist implements holistic elements to solve or prevent drug-related problems.

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“…These could help in the early detection and prevention of ADR. Furthermore, based on the spontaneous reporting and active surveillance systems ( 47 ), the pharmacovigilance and drug and therapeutics committee could assist in monitoring the quality and safe use of medicines to improve medication safety ( 48 ). Another important part of the clinical pharmacist's role is medication reconciliation and supporting patient adherence ( 49 ), especially in geriatrics.…”

Section: Discussionmentioning

confidence: 99%

A bibliometric analysis of global trends in the research field of pharmaceutical care over the past 20 years

Wang

Rao

Yin

et al. 2022

Front. Public Health

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Pharmaceutical care is essential in building up the basics of public health and clinical care. A comprehensive understanding of global status in the field of pharmaceutical care is necessary for directing its research frontiers and future trends. Therefore, this study aims to make a bibliometric analysis to track the development of pharmaceutical care research worldwide during the past two decades. The publications regarding pharmaceutical care were culled from the Web of Science Core Collection (WoSCC). Countries, institutions, authors, journals, references, and keywords in this field were visually analyzed by using VOSviewer (version 1.6.17) and CiteSpace (Version 5.8.R3). As a result, 3,597 publications (3,177 articles and 420 reviews) were obtained. The annual yields grew more than three times in the past two decades, from 54 records in 2002 to 379 papers in 2021. The United States played the leading role in this research from multiple aspects, including publication (n = 1,208), citations (n = 28,759), funding agencies, and collaboration worldwide. The University of Sydney in Australia was the most contributed institution with the greatest number of publications (n = 112) in pharmaceutical care research. Hersberger KE from the University of Basel was the most productive author (n = 40). Chen TF from the University of Sydney was the author who owed the highest H-index of 19 and most citations (n = 1,501). They both significantly impacted this field. American Journal of Health System Pharmacy produced the most publications, while Pharmacotherapy had the highest IF (IF2020 = 4.705) in this field. Clusters networks of co-cited references and keywords suggested that clinical pharmacy is an essential theme in pharmaceutical care. Terms of medication safety and critical care recognized by burst analysis of keywords also hint at the recent attention on clinical pharmacy. The present bibliometrics analysis may provide a comprehensive overview and valuable reference for future researchers and practitioners in the research field of pharmaceutical care.

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Improving medication safety in oncology care: impact of clinical pharmacy interventions on optimizing patient safety

Cited by 15 publications

References 26 publications

Impact of clinical pharmacists in an inpatient medical oncology service: A prospective study at a comprehensive cancer center in Jordan

Impact of clinical pharmacists in an inpatient medical oncology service: A prospective study at a comprehensive cancer center in Jordan

Comprehensive Medication Management Services with a Holistic Point of View, a Scoping Review

A bibliometric analysis of global trends in the research field of pharmaceutical care over the past 20 years

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