Iam very pleased to be presenting a new issue of Pediatric Critical Care Medicine (PCCM). Here are another three Editor's Choice articles, but with a difference. If there is a theme, it is that these articles with their supporting content and editorial materials, together provide a wealth of new clinically relevant information.The first article is about hyperoxia during cardiopulmonary bypass and its association with greater odds of morbidity and mortality (1). The second article reports a framework for compassionate end-of-life endotracheal extubation at home (2). My third choice describes the feasibility of implementing a new tool for serial neurologic assessment in pediatrics (SNAP) in critically ill patients (3). All three articles (1-3) and related editorial material (4-7) will be freely available for the next two months.