Improving Quality of Life for Patients with Angina Pectoris

Cupples, Margaret; Dempster, Martin

doi:10.2165/00115677-200109090-00002

Cited by 5 publications

(3 citation statements)

References 61 publications

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“…Improvements in the health-related quality of life of people with heart disease is an important consideration in the assessment of treatment effectiveness [13]. The MacNew questionnaire is a reliable and valid method of assessing changes in health-related quality of life among this population.…”

Section: Resultsmentioning

confidence: 99%

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Dempster

Donnelly

O’Loughlin

2004

Health Qual Life Outcomes

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BackgroundA previous review suggested that the MacNew Quality of Life Questionnaire was the most appropriate disease-specific measure of health-related quality of life among people with ischaemic heart disease. However, there is ambiguity about the allocation of items to the three factors underlying the MacNew and the factor structure has not been confirmed previously among the people in the UK.MethodsThe MacNew Questionnaire and the SF-36 were administered to 117 newly admitted patients to a tertiary referral centre in Northern Ireland. All patients had been diagnosed with ischaemic heart disease.ResultsA confirmatory factor analysis was conducted on the factor structure of the MacNew and the model was found to be an inadequate fit of the data. A quantitative and qualitative analysis of the items suggested that a five factor solution was more appropriate and this was validated by confirmatory factor analysis. This new structure also displayed strong evidence of concurrent validity when compared to the SF-36.ConclusionWe recommend that researchers should submit scores obtained from items on the MacNew to secondary analyses after being grouped according to the factor structure proposed in this paper, in order to explore further the most appropriate grouping of items.

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Section: Resultsmentioning

confidence: 99%

Untitled

Dempster

Donnelly

O’Loughlin

2004

Health Qual Life Outcomes

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“…26 The MacNew questionnaire is a reliable and valid method of assessing changes in health-related QoL among population with heart disease and discriminates better between angina grades. 27 , 28 …”

Section: Methodsmentioning

confidence: 99%

Sex differences in the quality of life of patients with acute coronary syndrome treated with percutaneous coronary intervention after a 3-year follow-up

Jankowska‐Polańska¹,

Uchmanowicz²,

Dudek³

et al. 2016

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BackgroundThe aims of this study were to analyze the dynamics of quality of life (QoL) changes after 36 months from the percutaneous coronary intervention (PCI) depending on sex and identify baseline predictors of the follow-up QoL of patients hospitalized for acute coronary syndrome (ACS) and subjected to PCI.Methods and resultsThe study included 137 patients, females (n=67) and males (n=70), with ACS who underwent PCI. The QoL was assessed using the MacNew Heart Disease Health-Related Quality of Life questionnaire. The group of females scored lower in all the domains of the MacNew Heart Disease Health-Related Quality of Life questionnaire in the initial measurement (B1), in the measurement after 6 months (B2), and in the long-term follow-up measurement (36 months – B3). Despite the fact that both groups achieved improved QoL, its values were higher in the males. The average growth rate of the QoL score in the period from the sixth month to 36th month was higher in females than in males. In the univariate and multivariate analyses, significant independent predictors with a negative influence on the long-term QoL score included female sex (ρ=−0.190, β=−0.21), age >60 years (ρ=−0.255, β=−0.186), and diabetes (ρ=−0.216, β=−0.216).ConclusionIn a 36-month follow-up of ACS patients treated with PCI, there were no statistically significant differences in QoL between sexes. In the entire cohort, there was improvement in QoL, which was higher in the case of the females studied. For the entire group, significant independent determinants of lower QoL 3 years after ACS included female sex, age >60 years, and diabetes.

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“…In fact, the coronary heart disease (CHD) annual mortality rate of 1270 per 100 000, in the age bracket of 45–75 years, is the highest in Europe [3]. Angina, a major CHD diagnostic category, is associated with reduced health‐related quality of life (HRQL) and increased anxiety and depression [4,5], and its management includes medication, surgery, psychological intervention and major lifestyle changes [6].…”

Section: Introductionmentioning

confidence: 99%