Today the water resources have a strategic impact in Bukhara region of Uzbekistan and about 95% of agricultural products produced in irrigated areas of the region. Conservation and efficient use of water resources is imperative. The goal of this research is to provide farmers scientific and practical recommendations on enhancing the soil leaching efficiency and improving the ameliorative condition of arable lands by using Biosolvent chemical compound during the soil leaching. Salts in the composition of the soil, especially soluble, have a serious impact on the development of crops, can dramatically reduce their yield.As a result of the analysis, the degree of soil salinity was determined: the soil is moderately saline, refers to chloride-sulfate salinization. When, soil leaching is carried out by Biosolvent chemical compound at the medium salted soils in Kagan district of Bukhara, the process of salt dissolution in soils accelerated and consumption of water used for soil leaching was saved up to 30% due to the enhancing the soil leaching efficiency.