Improving Skin Integrity in Babies Diagnosed with Neonatal Abstinence Syndrome

Bagwell, Gail A.; Thomas, A.; Ryshen, Greg

doi:10.1891/0730-0832.35.s1.1

Cited by 6 publications

(5 citation statements)

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“…In a recent study of vaginal flora, Farr et al observed significantly higher rates of candidiasis in pregnant mothers receiving medication assisted opioid treatment than in control groups [41]. Diaper dermatitis is a known condition common among infants with NAS, however, it is not considered a reliable diagnostic criterion [42]. Our data suggest that considerably more attention should be paid to potential links between dermatitis and vaginal candidiasis with NAS.…”

Section: Resultsmentioning

confidence: 62%

Characterization of Neonatal Abstinence Syndrome in Arizona from 2010-2017

Eaves

Barber

Whealy

et al. 2020

Preprint

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This study aimed to characterize the population of newborn infants with neonatal abstinence syndrome (NAS) and mothers who were opioid dependent at the time of giving birth, in Arizona. We analyzed approximately 1.2 million electronic medical records from the Arizona Department of Health Services Hospital Discharge Database to identify patterns and disparities across socioeconomic, ethnic/racial, and/or geographic groupings. In addition, we identified comorbid conditions that are differentially associated with NAS in infants or opioid dependence in mothers. Our analysis was designed to assess whether indicators such as race/ethnicity, insurance payer, marital status, and comorbidities are related to the use of opioids while pregnant. In this paper, we describe a population of mothers who are opioid dependent at the time of giving birth and infants who experience withdrawal due to opioid exposure in utero. While there have been studies of national trends in this population (see Patrick et al.), regional trends and issues are less well understood. Using data from the Arizona Department of Health Services Hospital Discharge Database, we find that women and infants who are non-Hispanic White and economically disadvantaged, tend be part of our populations of interest more frequently than expected. Additionally, we find that women who are opioid dependent at the time of giving birth are unmarried more often than expected, and we suggest that marital status could be a proxy for support. Finally, we report comorbidities, some of which have not been previously reported, associated with infants who have NAS and mothers who are opioid dependent.

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Section: Resultsmentioning

confidence: 62%

Characterization of Neonatal Abstinence Syndrome in Arizona from 2010-2017

Eaves

Barber

Whealy

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…In a recent study of vaginal flora, Farr et al observed significantly higher rates of candidiasis in pregnant mothers receiving medication assisted opioid treatment than in control groups [ 35 ]. Diaper dermatitis is a known condition common among neonates with NOWS, however, it is not considered a reliable diagnostic criterion [ 36 ]. Our data suggest that considerably more attention should be paid to potential links between dermatitis and vaginal candidiasis with NOWS.…”

Section: Discussionmentioning

confidence: 99%

Characterization of neonatal opioid withdrawal syndrome in Arizona from 2010-2017

et al. 2021

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In this paper, we describe a population of mothers who are opioid dependent at the time of giving birth and neonates exposed to opioids in utero who experience withdrawal following birth. While there have been studies of national trends in this population, there remains a gap in studies of regional trends. Using data from the Arizona Department of Health Services Hospital Discharge Database, this study aimed to characterize the population of neonates with neonatal opioid withdrawal syndrome (NOWS) and mothers who were opioid dependent at the time of giving birth, in Arizona. We analyzed approximately 1.2 million electronic medical records from the Arizona Department of Health Services Hospital Discharge Database to identify patterns and disparities across socioeconomic, ethnic, racial, and/or geographic groupings. In addition, we identified comorbid conditions that are differentially associated with NOWS in neonates or opioid dependence in mothers. Our analysis was designed to assess whether indicators such as race/ethnicity, insurance payer, marital status, and comorbidities are related to the use of opioids while pregnant. Our findings suggest that women and neonates who are non-Hispanic White and economically disadvantaged, tend be part of our populations of interest more frequently than expected. Additionally, women who are opioid dependent at the time of giving birth are unmarried more often than expected, and we suggest that marital status could be a proxy for support. Finally, we identified comorbidities associated with neonates who have NOWS and mothers who are opioid dependent not previously reported.

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“…Frequent rubbing or scrubbing of the perianal area due to more frequent bowel movements among NAS neonates may contribute to higher incidence of PD in this group. 30 However, avoiding frequent handling and disturbing of the NAS infant as per nonpharmacological approach leads to a longer exposure time between the soiled diaper and perianal skin. This strategy may also contribute significantly to the higher incidence and severity of PD in this group of infants.…”

Section: Perianal Dermatitismentioning

confidence: 99%