Improving Surface Plasmon Detection in Gold Nanostructures Using a Multi‐Polarization Spectral Integration Method

Lee, Kuang-Li; Chih, Min-Jian; Shi, Xu; Ueno, Kosei; Misawa, Hiroaki; Wei, Pei‐Kuen

doi:10.1002/adma.201202194

Cited by 21 publications

(16 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The slope of the fitting curve shows that the intensity sensitivity was 29,345%/RIU. The measured intensity sensitivity is much better than the reported intensity sensitivities of gold nanoslit, nanohole or nanogrid arrays ~1,010–12,963%/RIU273940 and ATR-based SPR sensors ~ 15,000%/RIU2. For the current system, the integration time for acquiring one spectrum was 25 milliseconds and the intensity noise was 0.7%.…”

Section: Resultsmentioning

confidence: 67%

Highly Sensitive Aluminum-Based Biosensors using Tailorable Fano Resonances in Capped Nanostructures

Lee

Hsu

You

et al. 2017

Sci Rep

Self Cite

View full text Add to dashboard Cite

Metallic nanostructure-based surface plasmon sensors are capable of real-time, label-free, and multiplexed detections for chemical and biomedical applications. Recently, the studies of aluminum-based biosensors have attracted a large attention because aluminum is a more cost-effective metal and relatively stable. However, the intrinsic properties of aluminum, having a large imaginary part of the dielectric function and a longer evanescent length, limit its sensing capability. Here we show that capped aluminum nanoslits fabricated on plastic films using hot embossing lithography can provide tailorable Fano resonances. Changing height of nanostructures and deposited metal film thickness modulated the transmission spectrum, which varied from Wood’s anomaly-dominant resonance, asymmetric Fano profile to surface plasmon-dominant resonance. For biolayer detections, the maximum surface sensitivity occurred at the dip of asymmetric Fano profile. The optimal Fano factor was close to −1.3. The wavelength and intensity sensitivities for surface thickness were up to 2.58 nm/nm and 90%/nm, respectively. The limit of detection (LOD) of thickness reached 0.018 nm. We attributed the enhanced surface sensitivity for capped aluminum nanoslits to a reduced evanescent length and sharp slope of the asymmetric Fano profile. The protein-protein interaction experiments verified the high sensitivity of capped nanostructures. The LOD was down to 236 fg/mL.

show abstract

Section: Resultsmentioning

confidence: 67%

Highly Sensitive Aluminum-Based Biosensors using Tailorable Fano Resonances in Capped Nanostructures

Lee

Hsu

You

et al. 2017

Sci Rep

Self Cite

View full text Add to dashboard Cite

show abstract

“…The slope of the fitting curve shows that the intensity sensitivity was 29,345%/RIU. This measured intensity sensitivity is much higher than the reported intensity sensitivities of gold nanoslit, nanohole or nanogrid arrays: ~1000%/RIU–10,000%/RIU [ 18 , 22 , 38 ], and prism-based SPR sensors: ~15,000%/RIU [ 2 ]. In our measurement, using a simple while-light source and a cheap USB-based mini-spectrometer, the intensity noise was 0.7%.…”

Section: Resultsmentioning

confidence: 67%

“…The biolayer sensitivity is determined by wavelength sensitivity, evanescent length, and refractive index difference between the adsorbate monolayer and surrounding environment, and the intensity sensitivity. To improve the sensing capability of SPR sensors, many methods have been proposed, such as spectral integration analysis [ 15 , 16 , 17 , 18 ], thermal-annealing nanoimprint method [ 19 , 20 , 21 , 22 ], Fano coupling method [ 23 , 24 , 25 ], narrowing resonance bandwidth with oblique angle incidence [ 26 ], two-mode coupling between top and substrate resonances [ 27 ], oblique-angle-induced Fano resonances [ 13 ], and nearly guided wave SPR sensors [ 28 ]. Among these approaches, the Fano resonance is frequently utilized to increase the intensity sensitivity in metallic nanostructures.…”

Section: Introductionmentioning

confidence: 99%

Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods

Lee

Hsu

et al. 2017

Sensors

Self Cite

View full text Add to dashboard Cite

We propose two approaches—hot-embossing and dielectric-heating nanoimprinting methods—for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy. Low-cost, large-area, and highly sensitive aluminum nanostructures on A4 size plastic films are fabricated by evaporating aluminum film on hot-embossing nanostructures. The narrowest bandwidth of the Fano resonance is only 2.7 nm in the visible light region. The periodic aluminum nanostructure achieves a figure of merit of 150, and an intensity sensitivity of 29,345%/RIU (refractive index unit). The rapid fabrication is also achieved by using radio-frequency (RF) sensitive plastic films and a commercial RF welding machine. The dielectric-heating, using RF power, takes advantage of the rapid heating/cooling process and lower electric power consumption. The fabricated capped aluminum nanoslit array has a 5 nm Fano linewidth and 490.46 nm/RIU wavelength sensitivity. The biosensing capabilities of the metallic nanostructures are further verified by measuring antigen–antibody interactions using bovine serum albumin (BSA) and anti-BSA. These rapid and high-throughput fabrication methods can benefit low-cost, highly sensitive biosensors and other sensing applications.

show abstract

“…This ability results in a strong enhancement of local electric fields, which is extremely useful for sensing [2][3][4][5][6][7], enhanced optical nonlinearity [8,9], plasmonic laser [10], and light harvesting [11]. Commercially available surface plasmon refractive index (RI) sensors are so far dominated by those based on propagating surface plasmon resonance (PSPR).…”

Section: Introductionmentioning

confidence: 99%

Dislocated Double-Layered Metal Gratings: Refractive Index Sensors with High Figure of Merit

et al. 2015

View full text Add to dashboard Cite

We experimentally demonstrate an enhanced refractive index sensing using a dislocated double-layered metal grating (DDMG). The DDMG is capable of supporting a novel guided mode caused by the interaction between localized surface plasmon resonances (LSPRs) from the individual gold stripes and Wood's anomaly in the dielectric grating layer between two gold gratings. We show that this guided mode can only be induced and mediated by the coupling of lattice plasmon resonances sustained by upper and lower gold grating through introducing a lateral displacement between the two gold gratings. The DDMG provides an experimental figure of merit (FOM) value up to 36 under normal incidence, which is superior to those of most of nanoplasmonic sensors relying on Fano resonances. Additionally, the DDMGs can be fabricated by a very simple and cost-effective method via a combination of two-beam interference lithography and metal deposition. Accompanied with high FOM and simple detection scheme, this sensor will be found in a wide range of applications in biomedical sensing.

show abstract

Improving Surface Plasmon Detection in Gold Nanostructures Using a Multi‐Polarization Spectral Integration Method

Cited by 21 publications

References 30 publications

Highly Sensitive Aluminum-Based Biosensors using Tailorable Fano Resonances in Capped Nanostructures

Highly Sensitive Aluminum-Based Biosensors using Tailorable Fano Resonances in Capped Nanostructures

Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods

Dislocated Double-Layered Metal Gratings: Refractive Index Sensors with High Figure of Merit

Contact Info

Product

Resources

About