Improving the accuracy of computational fluid dynamics simulations of coiled cerebral aneurysms using finite element modeling

Fillingham, Patrick; Bhathal, Julia Romero; Marsh, Laurel; Barbour, Michael; Kurt, Mehmet; Ionita, Ciprian N.; Davies, Jason M; Aliseda, Alberto; Levitt, Michael R.

doi:10.1016/j.jbiomech.2023.111733

Cited by 4 publications

(1 citation statement)

References 35 publications

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“…15 To address this limitation, Damiano et al 16 introduced a novel coil deployment technique utilizing the finite element method (FEM) that replicated the non-uniform distribution of coils within the aneurysm and enabled the prediction of post-treatment hemodynamics, which was supported by clinical studies. Patrick et al 17 demonstrated that using FEM technology can enhance the accuracy of CFD simulations of coils within intravascular aneurysms. Therefore, the combination of FEM and CFD holds significant potential for research on cerebral aneurysms.…”

Section: Introductionmentioning

confidence: 99%

Hemodynamic study on the therapeutic effects of varying diameter embolic coils in the treatment of intracranial aneurysms

Ren,

Li,

et al. 2024

Numer Methods Biomed Eng

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Endovascular coiling is the predominant method for treating cerebral aneurysms. Extensive reports on selecting coil length, hardness, and material are available. However, the impact of coil diameter on postoperative outcomes remains unclear. This study enrolled six personalized geometric models of intracranial aneurysms: three bifurcation aneurysms and three sidewall aneurysms. Four coil models were constructed by changing the coil diameter. Coil embolization was simulated using the finite element method. Computational fluid dynamics was used to characterize hemodynamics in the aneurysms after embolization. Evaluation parameters included velocity reduction, wall shear stress (WSS), low WSS (LWSS), oscillatory shear index (OSI), relative residence time (RRT), and residual flow volume in the aneurysms. At the peak time (t = 0.17 s), the proportion of LWSS area in bifurcation aneurysms increase with the rise in coil diameter: 0.8D, 71.28 ± 12.62% versus 1D, 74.97 ± 19.17% versus 1.2D, 78.88 ± 18.56% versus 1.4D, 84.00 ± 11.53% (mean ± SD). The proportion of high OSI area decreases as the coil diameter increases: 0.8D, 4.41% ± 2.82% versus 1.0D, 3.78 ± 3.33% versus 1.2D, 2.28% ± 1.77% versus 1.4D, 1.58% ± 1.11% (mean ± SD). The proportion of high RRT area increases as the coil diameter rises: 0.8D, 3.40% ± 1.68% versus 1.0D, 7.67 ± 4.12% versus 1.2D, 9.84% ± 9.50% versus 1.4D, 22.29% ± 14.28% (mean ± SD). Side wall aneurysms do not exhibit the aforementioned trend. Bifurcation aneurysms plugged with a coil of 1.4 times the diameter have the largest RFVs (<10 mm/s) within the group. Aforementioned patterns are not found in sidewall aneurysms. In the treatment of aneurysms with coiling, varying coil diameters can result in different hemodynamic environments within the aneurysm. Larger coil diameters have improved hemodynamic performance for bifurcation aneurysms. However, coil diameter and embolization effectiveness have no significant relationship for sidewall aneurysms.

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Section: Introductionmentioning

confidence: 99%

Hemodynamic study on the therapeutic effects of varying diameter embolic coils in the treatment of intracranial aneurysms

Ren,

Li,

et al. 2024

Numer Methods Biomed Eng

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Therapeutic Effect of Targeted Deployment Filling Coils in the Treatment of Intracranial Aneurysms

Ren,

Gao,

et al. 2024

Numer Methods Biomed Eng

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Endovascular coil embolization is the primary therapeutic modality for intracranial aneurysms. Substantial reports have been found regarding the coil packing density and inflow jet. However, the hemodynamic effect of increasing the rate of tamponade in the inflow jet area within the aneurysm remains unclear. In this study, individualized geometries of six intracranial aneurysms were recruited: all six aneurysms were located in the internal carotid artery. Two groups were created by changing the position and orientation of the microcatheter for the release of the third segment of the filling coil. The finite element method was used to simulate coil deployment. Computational fluid dynamics was used to characterize hemodynamics in post‐deployment aneurysms. The parameters evaluated included velocity reduction, wall shear stress (WSS), low WSS (LWSS), relative residence time (RRT), flow kinetic energy in the neck region of the aneurysms, and residual flow volume (RFV) in the aneurysms. At the peak time (t = 0.17 s), the targeted deployment group has similar proportion of LWSS area to conventional deployment groups: targeted 78.13% ± 34.59% versus normal 74.20% ± 36.94% (mean ± SD, p = 0.583). The targeted deployment group has a higher RRT area (targeted 16.84% ± 5.58% vs. normal 6.42% ± 5.67% [mean ± SD, p = 0.009]), smaller flow kinetic energy (targeted 9.43 ± 4.33 vs. normal 16.23 ± 5.92 [mean ± SD, p = 0.047]), and a larger RFV in the aneurysms (targeted 35.97 ± 24.35 mm3 vs. normal 25.80 ± 18.94 mm3 [mean ± SD, p = 0.44]). Inflow jets play an important role in the treatment of aneurysms, and deploying filling coils in accordance with inflow jets may result in a better hemodynamic environment.

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Odor emission pattern of the waste storage workshop of kitchen waste treatment plant and control strategy study with CFD simulation

Wei,

Wang,

Liu

et al. 2024

Environ Sci Pollut Res

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Improving the accuracy of computational fluid dynamics simulations of coiled cerebral aneurysms using finite element modeling

Cited by 4 publications

References 35 publications

Hemodynamic study on the therapeutic effects of varying diameter embolic coils in the treatment of intracranial aneurysms

Hemodynamic study on the therapeutic effects of varying diameter embolic coils in the treatment of intracranial aneurysms

Therapeutic Effect of Targeted Deployment Filling Coils in the Treatment of Intracranial Aneurysms

Odor emission pattern of the waste storage workshop of kitchen waste treatment plant and control strategy study with CFD simulation

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