Improving the biological properties of Fomes fomentarius MG835861 exopolysaccharide by bioincorporating selenium into its structure

Alvandi, Hale; Hatamian-Zarmi, Ashrafalsadat; Hosseinzadeh, Bahman Ebrahimi; Mokhtari-Hosseini, Zahra Beagom; Langer, Ewald; Aghajani, Hamed

doi:10.1016/j.carpta.2021.100159

Cited by 10 publications

(5 citation statements)

References 56 publications

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“…Furthermore, fungal fiber polysaccharides, such as chitin and chitosan, provide cardiovascular benefits by helping to lower cholesterol levels and supporting heart health [ 66 , 67 ]. The antioxidant effects of some fungal polysaccharides also play a role in fighting oxidative stress and chronic inflammation, contributing to the prevention of chronic diseases [ 56 , 68 ]. Additionally, the dietary fiber in mushrooms, including these polysaccharides, promotes digestive health by supporting the growth of beneficial gut bacteria and aiding digestion.…”

Section: Fungal Polysaccharidesmentioning

confidence: 99%

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Barcan,

Vamanu

2024

JoF

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This review evaluates the therapeutic effects of polysaccharides derived from mushroom species that have medicinal and edible properties. The fungal polysaccharides were recently studied, focusing on their modulation of the gut microbiota and their impact on various diseases. The study covers both clinical and preclinical studies, detailing the results and highlighting the significant influence of these polysaccharides on gut microbiota modulation. It discusses the potential health benefits derived from incorporating these polysaccharides into the diet for managing chronic diseases such as diabetes, neurodegenerative disorders, and cancer. Furthermore, the review emphasizes the interaction between fungal polysaccharides and the gut microbiota, underscoring their role in modulating the gut microbial community. It presents a systematic analysis of the findings, demonstrating the substantial impact of fungal polysaccharides on gut microbiota composition and function, which may contribute to their therapeutic effects in various chronic conditions. We conclude that the modulation of the gut microbiota by these polysaccharides may play a crucial role in mediating their therapeutic effects, offering a promising avenue for further research and potential applications in disease prevention and treatment.

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Section: Fungal Polysaccharidesmentioning

confidence: 99%

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Barcan,

Vamanu

2024

JoF

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“…Extracellular polysaccharides of Fomes fomentarius have a rather pronounced antioxidant activity (Alvandi et al, 2021). Zhang et al…”

Section: Antioxidant Featuresmentioning

confidence: 99%

“…Thus, supplements with Fomes fomentarius polysaccharides with added selenium have been established to enhance immune system function due to their antioxidant properties (Alvandi et al, 2021).…”

Section: Impact On the Immune Systemmentioning

confidence: 99%

Untitled

2023

Ukrainian journal of veterinary sciences

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“…Then the 8×8 mm nanofibers were immersed in each well (37 °C, 50 rpm). After 24 h, the above mixture was cultured on nutrient agar culture media (37 °C, 24 h) and the bacterial colonies were counted by colony counter (n=3) [31].…”

Section: Antibacterial Assaymentioning

confidence: 99%

In vivo study of beta-glucan-based biogenic synthesis of silver nanocomposite using Schizophyllum commune for wound dressings in a rat burn model

Safaee-Ardakani¹,

Hatamian-Zarmi²,

Sadat³

et al. 2022

Adv. Nat. Sci: Nanosci. Nanotechnol.

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Bacterial infection is a significant barrier to the natural wound healing process. Silver nanoparticles have antibacterial activity through the destruction of DNA and bacterial membranes. In the present study, a green method was introduced to synthesize silver nanoparticles produced by the Schizophyllum commune. The antibacterial mat loaded with 0.5, 1, and 3% (w/w) of bioactive silver nanoparticles were produced in polyvinyl alcohol (PVA) and schizophyllan (SPG) solution (20:80) with electrospun (PVA/SPG). Then the physicochemical properties of silver nanoparticles and the mats PVA/SPG containing silver nanoparticles were investigated. An animal model also examined antimicrobial activity, cytotoxicity, adhesion, and grade II burn ulcers. The results showed that spherical silver nanoparticles with a diameter of about 40 nm were produced and completely scattered on the nanofibers according to TEM images. A non-covalent interaction was revealed between SPG and AgNPs; the nanofibers were hydrophilic. Nanofibers containing silver nanoparticles had intense antimicrobial activity against E. coli and S. aureus. This inhibition increases with increasing concentration. The cytotoxicity and adhesion results showed that the PVA/SPG-AgNPs 1% sample had the best effect on fibroblast cells. The 1% sample was tested for the animal model, and after 14 days, it had a practical effect on the control. At 14 days post-treatment, a skinny epithelial layer was formed and covered the wound area, and these nanofibers were suitable for wound dressing. Consequently, PVA/SPG-AgNPs nanofibers could be a good option to cover burn wounds by speeding up the wound healing process and treatment costs.

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Improving the biological properties of Fomes fomentarius MG835861 exopolysaccharide by bioincorporating selenium into its structure

Cited by 10 publications

References 56 publications

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Untitled

In vivo study of beta-glucan-based biogenic synthesis of silver nanocomposite using Schizophyllum commune for wound dressings in a rat burn model

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