Improving the Degree of Functionalization and Solubility of Single-Walled Carbon Nanotubes via Covalent Multiple Functionalization

Wang, Feng; Deng, Kejian; Zhou, Li; Zhao, Jinbo; Ke, Xiaohuan; Wen, Lili

doi:10.1007/s10904-012-9689-5

“…Previous literature indicates that both pristine SWNT and COOH-SWNT are thermally stable below 600 ˚C. [20,21] Upon heating samples to this temperature and accounting for the removal of impurities such as excess solvent below 150 ˚C, we observe a 81.6% loss in mass. Based on previous literature, we attributed this mass loss to the combustion of amorphous carbon in the sample (Figure 2a).…”

Section: Improved Functionalization Density and Removal Of Amorphous ...mentioning

confidence: 62%

“…Previous literature indicates that both pristine SWNT and COOH-SWNT are thermally stable below 600 °C. 20,21 Upon heating samples to this temperature and accounting for the removal of impurities such as excess solvent below 150 °C, we observe a 81.6% loss in mass in the commercially-procured COOH-SWNT. On the basis of previous literature, we attributed this mass loss to the combustion of amorphous carbon in the sample (Figure 2a), suggesting the as-procured COOH-SWNT material is composed predominantly of amorphous carbon material not viable for delivery applications.…”

Section: Resultsmentioning

confidence: 92%

Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

Jackson

¹

,

Wang

²

,

González-Grandío

³

et al. 2021

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Nanomaterials have emerged as an invaluable tool for the delivery of biomolecules such as DNA and RNA, with various applications in genetic engineering and post-transcriptional genetic manipulation. Alongside this development, there has been an increasing use of polymer-based techniques, such as polyethyleneimine (PEI), to electrostatically load polynucleotide cargoes onto nanomaterial carriers. However, there remains a need to assess nanomaterial properties, conjugation conditions, and biocompatibility of these nanomaterial-polymer constructs, particularly for use in plant systems. In this work, we develop mechanisms to optimize DNA loading on single-walled carbon nanotubes (SWNTs) with a library of polymer-SWNT constructs and assess DNA loading ability, polydispersity, and both chemical and colloidal stability. Counterintuitively, we demonstrate that polymer hydrolysis from nanomaterial surfaces can occur depending on polymer properties and attachment chemistries, and describe mitigation strategies against construct degradation. Given the growing interest in delivery applications in plant systems, we also assess the toxicity of polymer-based nanomaterials in plants and provide recommendations for future design of nanomaterial-based polynucleotide delivery strategies.

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“…Based on previous literature, we attributed this mass loss to the combustion of amorphous carbon in the sample ( Figure 2a ). [20,22]…”

Section: Resultsmentioning

confidence: 99%

Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

Jackson

¹

,

Wang

²

,

González-Grandío

³

et al. 2021

Preprint

View full text Add to dashboard Cite

Nanomaterials have emerged as an invaluable tool for the delivery of biomolecules such as DNA and RNA, with various applications in genetic engineering and post-transcriptional genetic manipulation. Alongside this development, there has been an increasing use of polymer-based techniques, such as polyethyleneimine (PEI), to electrostatically load polynucleotide cargoes onto nanomaterial carriers. However, there remains a need to assess nanomaterial properties, conjugation conditions, and biocompatibility of these nanomaterial-polymer constructs, particularly for use in plant systems. In this work, we develop mechanisms to optimize DNA loading on single-walled carbon nanotubes (SWNTs) with a library of polymer-SWNT constructs and assess DNA loading ability, polydispersity, and both chemical and colloidal stability. Counterintuitively, we demonstrate that polymer hydrolysis from nanomaterial surfaces can occur depending on polymer properties and attachment chemistries, and describe mitigation strategies against construct degradation. Given the growing interest in delivery applications in plant systems, we also assess the toxicity of polymer-based nanomaterials in plants and provide recommendations for future design of nanomaterial-based polynucleotide delivery strategies.

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“…However, the expectations concerning their mechanical reinforcement potential have not been fully confirmed so far. This is mainly attributed to the difficulties of dispersing CNTs in polymer materials [5,6]. It is very difficult to disperse CNTs in most solvents as CNTs usually exist as ropes or bundles to form a highly dense structure [7,8].…”

Section: Introductionmentioning

confidence: 99%

Preparation of carbon nanotubes/polylactic acid nanocomposites using a non-covalent method

Li

¹

,

Song

²

,

Gao

³

et al. 2016

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The polymeric composites with four-armed star polylactic acid (PLA) immobilized on the surface of carbon nanotubes (CNTs) were constructed by a simple ultrasonic process using non-covalent method. The four-armed star polylactic acid was prepared by ring-opening polymerization of lactide using zinc ptetraaminophenylporphyrin (ZnP) as initiator and stannous octoate as catalyst. Due to the strong p-p interactions between CNTs and zinc porphyrin of star PLA, the CNTs/PLA composites can be easily obtained while the intrinsic graphitic structure of CNTs is retained. The CNTs/PLA nanocomposite was studied via infrared spectrum (IR) and thermogravimetric (TG) analysis. UV-Vis and fluorescence demonstrate that the porphyrin probably strongly anchored on the side walls of the nanotubes. Optical studies further promise the non-covalent interactions. Meanwhile, morphology studies with and scanning electron microscope (SEM) show that CNTs are dispersed well in the polymer. This convenient non-covalent method may be useful for the preparation of CNTs-polymer hybrid without the destruction of the intrinsic graphitic structure of the pristine CNTs.

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Improving the Degree of Functionalization and Solubility of Single-Walled Carbon Nanotubes via Covalent Multiple Functionalization

Cited by 8 publications

References 42 publications

Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

Preparation of carbon nanotubes/polylactic acid nanocomposites using a non-covalent method

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