Improving the drug compliance of hypertensive patients in primary care: importance of health education and self-management

Korzh, О.М.; Krasnokutskiy, S.; PANKOVA, Olena

doi:10.31688/abmu.2019.54.3.15

Cited by 8 publications

(7 citation statements)

References 22 publications

(22 reference statements)

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“…Despite that behavioral change is a highly effective prevention strategy, patient motivation and adherence to lifestyle recommendations are an obstacle to preventive care [12], [13]. A multifaceted approach at primary care settings, including controlled physical exercise, follow-up calls, and prescription reminders in addition to ongoing FP services, can improve patient adherence to prescribed medications and behavioral changes, while addressing barriers such as time and resource constraints for FPs [14], [15].…”

Section: Discussionmentioning

confidence: 99%

Knowledge and Application of Cardiovascular Disease Prevention Guidelines among Family Physicians: A Cross-sectional Study

Korzh

Nikolenko

Titkova

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Family physicians (FPs) play an important role in the prevention of cardiovascular disease (CVD). AIM: This study aims to assess the determinants of FPs’ knowledge and application of cardiovascular preventive management guidelines at primary health-care setting in Ukraine. MATERIALS AND METHODS: We performed a cross-sectional study conducted among the 226 FPs in Kharkiv Region, Ukraine. A self-administrated questionnaire was administered, exploring demographic, job characteristics, knowledge of CVD prevention guidelines, and application of CVD guidelines’ questions about the essential items related to diagnosis and management of CVD according to the international/local guidelines. RESULTS: The results show a very low level of knowledge of guidelines among FPs with 85.8% scoring below the acceptable knowledge level. The guidelines were applied below the acceptable level with 51.3% scoring below the cutoff point. The results indicate that both average scores were below the minimum acceptable level. Lack of knowledge of the CVD preventive care was considered the biggest barrier (62.8%). Lack of counseling skills was the second major barrier (37.9%). Subjectivity of the questions was considered to be the third barrier (32.6%). Lack of counseling skills was the second major barrier (37.9%). Subjectivity of the questions was considered to be the third barrier (32.6%). CONCLUSIONS: Recognizing the low level of knowledge and application of guidelines among primary care providers and working toward minimizing this problem can be through education, training, and monitoring of the application. This can potentially improve CVD preventive management among patients.

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Section: Discussionmentioning

confidence: 99%

Knowledge and Application of Cardiovascular Disease Prevention Guidelines among Family Physicians: A Cross-sectional Study

Korzh

Nikolenko

Titkova

et al. 2021

Open Access Maced J Med Sci

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“…Poor control of arterial hypertension in diabetic patients determines an elevated risk of acute cardiovascular events, such as myocardial infarction or stroke (24)(25)(26). GLP-1 agonists, such as exenatide and liraglutide, demonstrated in a meta-analysis a beneficial effect on reducing blood pressure in diabetic patients in the early phase of treatment, not related to weight reduction, probably by inhibition of the renin-angiotensin-aldosterone system, improvement of endothelial function and direct activation of specific receptors in the vascular tissue (27).…”

Section: Evidence Of Cardiovascular Effects Of Glp-1 Agonistsmentioning

confidence: 99%

Metabolic and cardiovascular benefits of GLP‑1 agonists, besides the hypoglycemic effect (Review)

et al. 2020

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Patients with type 2 diabetes exhibit higher cardiovascular risk than normal individuals. Optimal blood glucose levels are rarely achieved in diabetic patients. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as a new antidiabetic drug class with multiple metabolic effects. Some trials have evaluated their safety, but it has been recently demonstrated that this new class has cardiovascular benefits, through other mechanisms than glycemic control. The use of GLP-1RAs was associated with a significant reduction of cardiovascular and all-cause mortality, with a safe profile related to pancreatitis or thyroid cancer, as compared with placebo. This review presents the cardiovascular and metabolic benefits of GLP-1 RAs versus placebo, in patients with type 2 diabetes. Semaglutide and liraglutide demonstrated a reduction in cardiovascular events, with similar rates on cardiovascular mortality. Ongoing trials assess the cardiovascular benefits and side effects of dulaglutide treatment. Exenatide and liraglutide demonstrated the decrease of blood pressure values, weight reduction and improvement of dyslipidemia. Liraglutide induced, both in vivo and in vitro, an improvement of blood circulation, increasing the nitric oxide level and inhibiting the adhesion and procoagulant factors. Also, liraglutide demonstrated beneficial effects on cardiac remodeling after myocardial infarction, but more large trials are required. However, the international guidelines recommend using GLP-1 RAs as first-line therapy in type 2 diabetes patients with high cardiovascular risk or as first-line agents in patients intolerant to metformin. Contents 1. Introduction 2. Mechanism of action of GLP-1 hormone and its pleiotropic effects 3. Evidence of cardiovascular effects of GLP-1 agonists 4. Evidence of GLP-1 agonists on metabolism 5. Conclusions

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“…The existing system did not contribute to the reduction of self-referral to specialized medical services. Studies have confirmed that this situation may have a negative effect on the patient's treatment 33 .…”

Section: Discussionmentioning

confidence: 98%

Patients’ perceptions about access to health care and referrals to family physicians in Georgia

ვერულავა

Jorbenadze²,

Karimi

2020

Arch Balk Med Union

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Improving the drug compliance of hypertensive patients in primary care: importance of health education and self-management

Cited by 8 publications

References 22 publications

Knowledge and Application of Cardiovascular Disease Prevention Guidelines among Family Physicians: A Cross-sectional Study

Knowledge and Application of Cardiovascular Disease Prevention Guidelines among Family Physicians: A Cross-sectional Study

Metabolic and cardiovascular benefits of GLP‑1 agonists, besides the hypoglycemic effect (Review)

Patients’ perceptions about access to health care and referrals to family physicians in Georgia

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