We investigate the fading cognitive multiple access wiretap channel (CMAC-WT), in which two secondary-user transmitters (STs) send secure messages to a secondary-user receiver (SR) in the presence of an eavesdropper (ED) and subject to interference threshold constraints at multiple primaryuser receivers (PRs). We design linear precoders to maximize the average secrecy sum rate for multiple-input multiple-output (MIMO) fading CMAC-WT under finite-alphabet inputs and statistical channel state information (CSI) at STs. For this nondeterministic polynomial time (NP)-hard problem, we utilize an accurate approximation of the average secrecy sum rate to reduce the computational complexity, and then present a two-layer algorithm by embedding the convex-concave procedure into an outer approximation framework. The idea behind this algorithm is to reformulate the approximated average secrecy sum rate as a difference of convex functions, and then generate a sequence of simpler relaxed sets to approach the non-convex feasible set. Subsequently, we maximize the approximated average secrecy sum rate over the sequence of relaxed sets by using the convexconcave procedure. Numerical results indicate that our proposed precoding algorithm is superior to the conventional Gaussian precoding method in the medium and high signal-to-noise ratio (SNR) regimes.Index Terms-Finite-alphabet inputs, linear precoding, MIMO, statistical CSI, physical-layer security, cognitive multiple access wiretap channel.