Improving the electrochemical properties of polyamide 6/polyaniline electrospun nanofibers by surface modification with ZnO nanoparticles

André, Rafaela S.; Pavinatto, Adriana; Mercante, Luiza A.; Paris, E. C.; Mattoso, Luiz H. C.; Corrêa, Daniel S.

doi:10.1039/c5ra15588f

Cited by 51 publications

(19 citation statements)

References 43 publications

(42 reference statements)

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“…The micrographs suggest that the SDZ‐[Mg–Al]‐LDH particles did not form large agglomerates within the PLA nanofibers, meaning their proper distribution throughout the scaffold. This is a positive result because the scaffold can promote antimicrobial inhibition regardless of the side placed in contact with the wound …”

Section: Resultsmentioning

confidence: 98%

Electrospun poly(lactic acid) nanofibers loaded with silver sulfadiazine/[Mg–Al]‐layered double hydroxide as an antimicrobial wound dressing

Malafatti

Bernardo

Moreira

et al. 2020

Polymers for Advanced Techs

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Poly(lactic acid) (PLA) is a versatile, bioabsorbable, and biodegradable polymer with excellent biocompatibility and ability to incorporate a great variety of active agents. Silver sulfadiazine (SDZ) is an antibiotic used to control bacterial infection in external wounds. Aiming to combine the properties of PLA and SDZ, hydrotalcite ([Mg-Al]-LDH) was used as a host matrix to obtain an antimicrobial system efficient in delivering SDZ from electrospun PLA scaffolds intended for wound skin healing. The structural reconstruction method was successfully applied to intercalate silver sulfadiazine in the [Mg-Al]-LDH, as evidenced by X-ray diffraction and thermogravimetric analyses. Observations by scanning electron microscopy revealed a good distribution of SDZ-[Mg-Al]-LDH within the PLA scaffold. Kinetics studies revealed a slow release of SDZ from the PLA scaffold due to the intercalation in the [Mg-Al]-LDH. In vitro antimicrobial tests indicated a significant inhibitory effect of SDZ-[Mg-Al]-LDH against Escherichia coli and Staphylococcus aureus. This antibacterial activity was sustained in the 2.5-wt% SDZ-[Mg-Al]-LDH-loaded PLA nanofibers, which also displayed excellent biocompatibility towards human cells. The multifunctionality of the PLA/SDZ-[Mg-Al]-LDH scaffold reported here is of great significance for various transdermal applications. K E Y W O R D S drug release, electrospinning, hydrotalcite, sulfadiazine silver, wound healing

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Section: Resultsmentioning

confidence: 98%

Electrospun poly(lactic acid) nanofibers loaded with silver sulfadiazine/[Mg–Al]‐layered double hydroxide as an antimicrobial wound dressing

Malafatti

Bernardo

Moreira

et al. 2020

Polymers for Advanced Techs

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“…[14,15]. Electrospun nanofibers, for instance, present 3D structures with large surface area and porosity [16][17][18], whose surface can be further modified with varied materials, including carbon materials. Carbon materials display excellent characteristics, such as low cost, wide window of electrical potential and good electrocatalytic activity [19].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical sensor based on polyamide 6/polypyrrole electrospun nanofibers coated with reduced graphene oxide for malathion pesticide detection

Migliorini

Sanfelice

Mercante

et al. 2019

Mater. Res. Express

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An electrochemical sensor based on polymeric electrospun nanofibers of polyamide 6 (PA6)/ polypyrrole (PPy) surface-modified with two forms of graphene was developed for the detection of malathion, an organophosphorus pesticide. The materials were chosen considering the electrospun nanofibers possess large surface area and porosity, while reduced graphene oxide has remarkable electrical conductivity, which is a good strategy to increase sensor sensitivity and improve the limit of detection towards the pesticide. The surface modification of nanofibers with graphene was carried out using chemically (CRGO) and electrochemically reduced graphene oxide (ERGO), in order to demonstrate how the degree of reduction of graphene oxide can influence its electrical conductivity. The influence of the reduction on the conductivity properties of graphene-based films was studied through electrochemical techniques: cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The platform modified with CRGO, which presented higher electrical conductivity compared to ERGO, was used in the electrochemical detection of the pesticide malathion and exhibited a low detection limit of 0.8 ng ml −1 (S/N=3). The results indicate that chemically reduced graphene oxide is a potential alternative for modifying electrodes surfaces designed for sensing distinct pollutants of environmental or agricultural interest.

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“…Sensing layers fabricated with nanomaterials have demonstrated good performance in terms of the detection of varied analytes, even at very low concentrations [20][21][22]. Electrospun nanofibers, for instance, have been applied as sensing layers aiming to increase the high surface area/volume ratio, leading to a higher interaction with the analytes under investigation [23,24]. In order to increase the detection efficiency of impedimetric e-tongues, nanofibers surface can be functionalized with metal nanoparticles [23] and carbon-based nanomaterials [15].…”

Section: Introductionmentioning

confidence: 99%

Tuning the Electrical Properties of Electrospun Nanofibers with Hybrid Nanomaterials for Detecting Isoborneol in Water Using an Electronic Tongue

et al. 2019

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The presence of contaminants in water is a subject of paramount importance nowadays, which can make water improper to human consumption even when these contaminants are present at very low concentrations, causing health issues and economic losses. In this work, we evaluated the performance of nanocomposites based on nylon 6,6/chitosan electrospun nanofibers modified by cellulose nanowhiskers combined with functional materials like silver nanoparticles, gold nanoparticles, and reduced graphene oxide to be used as sensing layers of an electronic tongue (e-tongue) to detect Isoborneol. This compound, found in some plants and essential oils, is used as a natural repellent and also to produce many other chemicals. Additionally, its chemical structure is related to that of 2-methylisoborneol, a critical pollutant in aqueous media. The synergism between the nanomaterials combined with electrospun nanofibers could be verified by the enhancement of the charge transference ability. Additionally, electrical capacitance data measured with the impedimetric e-tongue were treated by Principal Component Analysis (PCA), and revealed the sensing system was able to discriminate samples contaminated with Isoborneol at nanomolar concentrations. Moreover, the electronic tongue system could detect Isoborneol in real water samples under different concentrations.

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Improving the electrochemical properties of polyamide 6/polyaniline electrospun nanofibers by surface modification with ZnO nanoparticles

Abstract: ZnO nanoparticles adsorbed onto electrospun nanofiber surfaces improve the electron transfer kinetics and increase the electrode electroactive area. The modified electrodes can be a potential platform for electrochemical applications.

Cited by 51 publications

References 43 publications

Electrospun poly(lactic acid) nanofibers loaded with silver sulfadiazine/[Mg–Al]‐layered double hydroxide as an antimicrobial wound dressing

Electrospun poly(lactic acid) nanofibers loaded with silver sulfadiazine/[Mg–Al]‐layered double hydroxide as an antimicrobial wound dressing

Electrochemical sensor based on polyamide 6/polypyrrole electrospun nanofibers coated with reduced graphene oxide for malathion pesticide detection

Tuning the Electrical Properties of Electrospun Nanofibers with Hybrid Nanomaterials for Detecting Isoborneol in Water Using an Electronic Tongue

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