In this paper, a hybrid methodology based on modi¯ed nodal analysis (MNA) and genetic algorithm (GA) is presented for simpli¯ed symbolic small-signal analysis of analog circuits containing semiconductor devices like MOSFETs. At¯rst, the circuit is analyzed by the MNA, and the derived exact continuous-time transfer function is automatically simpli¯ed via GA. We propose a new multi-objective criterion for symbolic simpli¯cation of continuous-time transfer functions, which can be performed by such optimization algorithms as local-search algorithms, heuristic algorithms, swarm-intelligence algorithms, etc. In this paper, GA is used to validate the proposed simpli¯cation criterion. All processes including netlist text pre-processing, symbolic analysis via MNA, post-processing, and simpli¯cation via GA are consecutively run in an m-¯le MATLAB program. The comparison of obtained numeric results with HSPICE demonstrates the e±ciency of the proposed methodology.