2018
DOI: 10.1016/j.kint.2018.02.006
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Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Abstract: Patients with severely decreased glomerular filtration rate (GFR) (i.e., chronic kidney disease [CKD] G4+) are at increased risk for kidney failure, cardiovascular disease (CVD) events (including heart failure), and death. However, little is known about the variability of outcomes and optimal therapeutic strategies, including initiation of kidney replacement therapy (KRT). Kidney Disease: Improving Global Outcomes (KDIGO) organized a Controversies Conference with an international expert group in December 2016 … Show more

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Cited by 87 publications
(67 citation statements)
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“…Previous studies have asserted a direct correlation between pre-admission creatinine level and mortality rate in patients undergoing CRRT (38,39). However, neither pre-dialysis nor post-dialysis serum creatinine levels were significantly associated with mortality rate in this study.…”
Section: Discussioncontrasting
confidence: 80%
“…Previous studies have asserted a direct correlation between pre-admission creatinine level and mortality rate in patients undergoing CRRT (38,39). However, neither pre-dialysis nor post-dialysis serum creatinine levels were significantly associated with mortality rate in this study.…”
Section: Discussioncontrasting
confidence: 80%
“…In particular, retarding dialysis start is a major clinical and economical goal of Nephrology care. The international expert panel of Kidney Disease: Improving Global Outcomes (KDIGO) Guidelines has repeatedly brought to attention of nephrology community the importance of conservative care as rational treatment alternative to dialysis even in advanced CKD because dialysis initiation associates with a still dramatically increase in mortality, poorer quality of life in survivors, and striking hike of economic costs …”
Section: Discussionmentioning
confidence: 99%
“…Interventions aimed at giving feedback and discussing the HRQoL outcomes face-to-face with the individual patient have been studied within oncology and diabetes care [ 2 , 3 ]. Person-centered care and patient partnership have been increasingly highlighted as an important factor in improving health care quality [ 4 ]. Patient-reported outcome measures (PROMs) have the potential to be a useful tool in achieving this.…”
Section: Introductionmentioning
confidence: 99%