Abstract. Object-oriented models of the object and the control system, based on data ware and software improvement, for elements of the computer-integrated control system designed for a heat supply system, have been worked out. Also, a complex criterion of optimal control of the heat supply system structure on the basis of engineering-and-economic performance, as well as control algorithms defining the optimal structure of the system and using genetic algorithms, have been proposed. Research of the control efficiency using a simulation model of the heat supply system has been carried out. Keywords: computer-integrated control system, structure variation control, optimal control criterion, object-oriented analysis, engineering-and-economic performance, genetic algorithm.