Improving the therapeutic value of sutures

Duarte-Peña, Lorena; Fragoso-Medina, Amira J.; Bucio, Emilio; López‐Saucedo, Felipe

doi:10.1016/b978-0-12-819750-9.00003-6

Advanced Technologies and Polymer Materials for Surgical Sutures 2023

DOI: 10.1016/b978-0-12-819750-9.00003-6

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Improving the therapeutic value of sutures

Lorena Duarte-Peña¹,

Amira J. Fragoso-Medina²,

Emilio Bucio³

et al.

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2024

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Cited by 1 publication

References 80 publications

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Bioinspired Hydro- and Hydrothermally Responsive Tubular Soft Actuators

Zhang,

Aziz,

Salahuddin

et al. 2024

ACS Appl. Mater. Interfaces

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Soft actuators made of thermoresponsive polymers have great potential for intelligent robotics and biomedical devices due to their reversible deformation capability in response to temperature fluctuations. However, they are constrained by a predefined phase transition temperature, limited directional deformation, and nonbiocompatible formulations, thereby restricting their practical utility. Herein a new biomimicry approach is presented to overcome these limitations by developing hydroand hydrothermally responsive soft actuators made of biocompatible and pliable materials i.e. cotton yarn and polyurethane. We mimic the tubular shape of elephant trunks with their unique muscle orientation by embedding a helical cotton yarn within a hydrophilic polyurethane tube, followed by targeted surface patterning. Unlike the narrowrange shape morphing across the phase transition temperature boundary of typical thermoresponsive hydrogel actuators, we harness hydrothermal stiffness variations in polyurethane to obtain consistent morphing capabilities over a much wider temperature range. The developed actuators can perform versatile activities such as linear, bending, curvilinear, and rotating movements, overcoming the unidirectional motion limitations of conventional soft actuators. The cell viability assay on the building block materials also confirms the high biocompatibility of the actuators. The reported facile fabrication strategy provides new insights for designing complex yet free-standing soft actuators from readily available supple materials.

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Bioinspired Hydro- and Hydrothermally Responsive Tubular Soft Actuators

Zhang,

Aziz,

Salahuddin

et al. 2024

ACS Appl. Mater. Interfaces

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show abstract

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Improving the therapeutic value of sutures

Cited by 1 publication

References 80 publications

Bioinspired Hydro- and Hydrothermally Responsive Tubular Soft Actuators

Bioinspired Hydro- and Hydrothermally Responsive Tubular Soft Actuators

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