Central neuraxial blockade (CNB) describes a range of procedures that are used to provide perioperative anaesthesia and/or analgesia for patients undergoing a wide variety of surgical procedures. It represents a significant proportion of workload for both anaesthetists and those in training. The most effective method(s) for teaching and training novice anaesthetists to perform CNB remains unclear. This paper presents a systematic review of the literature and recommendations for educational techniques in clinical practice. A systematic review of the literature was undertaken. Medline, PubMed, ERIC, Cochrane library, PsycInfo, and HMIC databases were searched from inception to June 2018 for studies involving CNB skills teaching. Searches were limited to the English language and full text availability. Studies were analysed and quality scored using the MERSQI scale [1]. Outcomes for each intervention were also plotted against a modified Kirkpatrick's model. 14 papers (n=14) were included in the review. The mean MERSQI score was 12.43 (range 8.5-16). 9 of the studies had a MERSQI score above 12. The studies reported a range of educational and clinical outcomes; the modal outcome was improved knowledge and/or skills (2b). Interventions identified were the use of Ultrasound (2 studies), Educational multimedia (4 studies), Simulation (8 studies), Feedback delivery (1 study), Mental imagery (1 study), and Learning curves (1 study). The use of ultrasound imaging and simulated clinical practice demonstrated the most significant effects on trainee knowledge and skill; however, studies were generally small, and as both methods and outcomes showed marked heterogeneity, large scale, high quality studies would be beneficial to this important aspect of anaesthetic practice.