Impulse Oscillometry in the Diagnosis of Airway Resistance in Chronic Obstructive Pulmonary Disease

Piorunek, Tomasz; Kostrzewska, Magdalena; Cofta, Szczepan; Batura‐Gabryel, Halina; Andrzejczak, P.; Bogdański, Paweł; Wysocka, Ewa

doi:10.1007/5584_2014_49

Cited by 22 publications

(15 citation statements)

References 14 publications

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“…In all COPD subjects, R5–R20 had a stronger correlation with FVC, FEV 1 , FEV 1 /FVC, and MMEF ( r =−0.491, −0.628, −0.572, and −0.588, respectively) than X5 ( r =0.415, 0.561, 0.517, and 0.555, respectively). Piorunek et al18 showed that the severity of bronchial obstruction, as assessed by spirometry (FEV 1 %predicted), correlates with the measures obtained using the oscillometric method. The correlation between the FEV 1 %predicted and oscillometric measurements (R5, R5–R20, and X5) was significant ( r =−0.62, −0.80, and 0.75, respectively; P <0.05).…”

Section: Discussionmentioning

confidence: 99%

Clinical application value of impulse oscillometry in geriatric patients with COPD

Liu

2017

COPD

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BackgroundThe diagnosis and assessment of COPD rely mainly on the use of spirometry, which is an effort-dependent test and requires good patient cooperation. Impulse oscillometry (IOS) is a non-volitional method that requires less effort and cooperation and presents advantages for geriatric patients. However, the clinical application value of IOS in geriatric patients with COPD remains unclear.AimThe aim of this study was to investigate the clinical application value of IOS in geriatric patients with COPD.Subjects and methodsA total of 234 subjects were retrospectively enrolled in this study, including 133 patients with COPD and 101 healthy volunteers. All the participants underwent IOS and spirometry examination. The data were collected and analyzed in the overall group, the geriatric group (aged ≥65 years), and the advanced elderly group (aged ≥80 years).Results1) In COPD patients, a significant increase in respiratory impedance (Z5), resonant frequency (Fres), and respiratory resistance (R5, R20, R5–R20) and a decrease in respiratory reactance (X5) were observed in the overall group, the geriatric group, and the advanced elderly group compared with the healthy control subjects. 2) The IOS parameters correlated well with spirometry in COPD. In particular, R5–R20 showed the best correlation with forced expiratory volume in 1 second (FEV1) in the different age groups. 3) Fres and R5–R20 had the best diagnostic efficiency for COPD. The area under the curve (AUC) values for Fres, expressed by the receiver operating characteristic (ROC) curve, were 0.905, 0.909, and 0.914, for the different age groups, respectively. 4) The optimal cutoff values for Fres to diagnose airflow obstruction from ROC curves was 17.715 in the COPD patients. Its sensitivity and specificity were 0.789 and 0.931, respectively, and the cutoff values were similar in geriatric and advanced elderly patients.ConclusionIOS demonstrated good relevance compared with spirometry for geriatric patients with COPD. IOS may serve as an alternative method for spirometry in elderly subjects for the evaluation of the state of COPD.

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Section: Discussionmentioning

confidence: 99%

Clinical application value of impulse oscillometry in geriatric patients with COPD

Liu

2017

COPD

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“…(R5-R20)%R5 indicates the proportion of peripheral airway resistance to total airway resistance. [ 13 ] Reactance at 5 Hz (X5) relates to the physical properties of the lung parenchyma and its ability to expand and facilitate alveolar filling. Frequency response (Fres) is the point at which reactance is zero (when forces of inertia and capacitance are equal).…”

Section: Introductionmentioning

confidence: 99%

“…Fres and Ax are now considered sensitive indicators of reactive airflow limitation. [ 13 ] IOS parameters are more sensitive to bronchial provocation test, and bronchodilation test as compared to the traditional PFTs. [ 14 – 16 ] However, the relationship between IOS index and traditional PFTs, and the diagnostic role of IOS parameters in COPD patients on inhaled glucocorticoid or roflumilast therapy is not well-characterized.…”

Section: Introductionmentioning

confidence: 99%

Impulse oscillometry system as an alternative diagnostic method for chronic obstructive pulmonary disease

et al. 2017

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We aimed to compare impulse oscillation system (IOS) and traditional pulmonary function tests (PFTs) for the assessment of the severity of chronic obstructive pulmonary disease (COPD), and to assess the use of IOS parameters to identify patients who were forced expiratory volume in 1 second (FEV1)%pred < 50%.Patients with COPD (n = 215) were enrolled at the Ninth Hospital of Xi’an Affiliated Hospital of Xi’an Jiaotong University between October 2014 and September 2016. All patients were assessed by traditional PFT and IOS. Diagnostic performance of IOS parameters to determine indication for patients of FEV1%pred < 50% was assessed on receiver-operating characteristics (ROC) curve analysis.Out of 215 patients, 18, 83, 78, and 36 patients were classified as grade 1, 2, 3, and 4, respectively, according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) severity grading. On Spearman correlation analysis, FEV1%pred, MMEF 75%–25%, and residual volume/total lung capacity (RV/TLC) correlated with total respiratory impedance (Z5)%pred, resistance at 5 Hz (R5)-resistance at 20 Hz (R20), R5-R20% R5, R5, R5%pred, frequency response (Fres), reactance area (Ax), and reactance at 5 Hz (X5). On ROC curve analysis, the area under the curve (AUC) of X5 absolute value, Fres, Ax, Z5%pred, R5-R20, and R5-R20% R5 were 0.748, 0.755, 0.760, 0.705, 0.715, and 0.735, respectively, for COPD patients who required inhalational glucocorticoid therapy.IOS parameters showed a good correlation with traditional pulmonary function parameters; reactance parameters showed a stronger correlation than that of the resistance parameters. IOS can be used as an alternative method for pulmonary function assessment in patients with COPD with FEV1%pred < 50% who need inhalational glucocorticoid therapy.Clinical trial registration number: ChiCTR-OCH-14004904.

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“…Определить реальные значения эластического и инерционного сопротивлений нельзя, но по их суммарной величине (компоненту Х) можно судить о преобладании того или другого сопротивления при разных частотах. Метод показал высокую информативность для диагностики и контроля лечения обструктивных заболеваний легких у взрослых и детей, бóльшую чувствительность в выявлении периферической обструкции дыхательных путей, чем спирометрия [19][20][21]. В единичных исследованиях метод форсированных осцилляций применяли для оценки влияния наркоза во время операций на механику дыхания [22,23].…”

Section: Introductionunclassified

The impulse oscillometry technique in patients with pulmonary tuberculosis in pre- and post-operative surgical treatment

2019

MedAlliance

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В связи с ростом числа больных с лекарственно устойчивым туберкулезом все чаще требуется включать хирургический этап в лечение данной категории пациентов. Оценка вентиляционной функции легких с помощью общепринятых методов исследования, требующих максимальных и форсированных дыхательных маневров, в раннем послеоперационном периоде невозможна. В связи с этим для контроля проходимости дыхательных путей после хирургического вмешательства был предложен метод импульсной осциллометрии (ИО), для которого достаточно обычного спокойного дыхания. Цель исследования: выявить особенности изменений параметров импульсной осциллометрии у больных с туберкулезом легких с разным объемом резекции легких в раннем послеоперационном периоде. Материалы и методы. Обследовано 73 пациента с туберкулезом легких, которым были проведены 22 сегментэктомии, 27 лобэктомий, 24 пневмонэктомии. Исходно параметры вентиляции оценивались методами спирометрии и бодиплетизмографии, ИО выполнялась до и через 7–10 дней после операции. Результаты. В раннем послеоперационном периоде достоверно изменилось реактивное сопротивление на частоте 5 Гц, связанное с повышением эластического сопротивления в группах сегмент- и лобэктомий. Анализ средних отклонений после операции показал повышение общего дыхательного сопротивления и его резистивного компонента на частоте 5 Гц во всех группах. Резистанс на частоте 20 Гц в группах сегмент- и лобэктомий снизился, после пневмонэктомий повысился. Заключение. В раннем послеоперационном периоде при сегмент- и лобэктомиях наблюдалось ухудшение проходимости периферических дыхательных путей при снижении сопротивления центральных отделов. В группе пневмонэктомий резистивное сопротивление возрастало и в периферических и в центральных дыхательных путях.

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Impulse Oscillometry in the Diagnosis of Airway Resistance in Chronic Obstructive Pulmonary Disease

Cited by 22 publications

References 14 publications

Clinical application value of impulse oscillometry in geriatric patients with COPD

Clinical application value of impulse oscillometry in geriatric patients with COPD

Impulse oscillometry system as an alternative diagnostic method for chronic obstructive pulmonary disease

The impulse oscillometry technique in patients with pulmonary tuberculosis in pre- and post-operative surgical treatment

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