2022
DOI: 10.1016/j.ijbiomac.2022.08.117
|View full text |Cite
|
Sign up to set email alerts
|

In-depth investigation of the hypoglycemic mechanism of Morchella importuna polysaccharide via metabonomics combined with 16S rRNA sequencing

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

1
3
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
8
1
1

Relationship

0
10

Authors

Journals

citations
Cited by 20 publications
(6 citation statements)
references
References 50 publications
1
3
0
Order By: Relevance
“…Te signifcant decrease of IL-1β levels in the BQP group mice also proved this inference. In addition to the decrease in pathogenic bacteria, the increased abundance of Dubosiella, Akkermansia, and Faecalibaculum could be thought to lead to an increase in the content of SCFAs in BQP group mice, as the previous studies reported [37][38][39][40]. In the present study, BQP intervention signifcantly increased SCFA content in diabetic mice, which may lead to improvement of islet cell dysfunction and insulin resistance [41].…”
Section: Discussionsupporting
confidence: 62%
“…Te signifcant decrease of IL-1β levels in the BQP group mice also proved this inference. In addition to the decrease in pathogenic bacteria, the increased abundance of Dubosiella, Akkermansia, and Faecalibaculum could be thought to lead to an increase in the content of SCFAs in BQP group mice, as the previous studies reported [37][38][39][40]. In the present study, BQP intervention signifcantly increased SCFA content in diabetic mice, which may lead to improvement of islet cell dysfunction and insulin resistance [41].…”
Section: Discussionsupporting
confidence: 62%
“…The genus Dubosiella increased vastly from 0.14% in a blank control group to 19.67% in HB jujube fruit polysaccharides, and Bacillus increased from 0.47% to 13.38%. The genus Dubosiella has been reported to increase in the treatment of some diseases, such as sepsis-associated encephalopathy [ 32 ], type 2 diabetes mellitus [ 33 ], and rheumatoid arthritis [ 34 ]. In comparison, the genus Bacillus was considered one important kind of probiotic [ 35 ].…”
Section: Resultsmentioning
confidence: 99%
“…Metzler [53] through their study confirmed that there is a correlation between serum metabolite changes and RFI variation in chickens, and serum metabolite variation can be used to predict changes The liver is the largest parenchymal organ in chickens. By analyzing the transcriptome of livers, we can gain a deeper understanding of the dynamic processes of gene expression and reveal gene regulatory networks related to metabolism, immunity, and growth [54] . Xu [55] conducted transcriptome sequencing of liver tissues from chickens with different feed efficiency and found that the DEGs in the liver were mainly associated with appetite, cellular activity, and lipid metabolism.…”
Section: Discussionmentioning
confidence: 99%