2023
DOI: 10.3389/fmed.2023.1272900
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In focus: perplexing increase of urinary stone disease in children, adolescent and young adult women and its economic impact

Guido Filler,
Sumit Dave,
Victor Ritter
et al.

Abstract: BackgroundUrinary stone disease (USD) historically has affected older men, but studies suggest recent increases in women, leading to a near identical sex incidence ratio. USD incidence has doubled every 10 years, with disproportionate increases amongst children, adolescent, and young adult (AYA) women. USD stone composition in women is frequently apatite (calcium phosphate), which forms in a higher urine pH, low urinary citrate, and an abundance of urinary uric acid, while men produce more calcium oxalate ston… Show more

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