Various situations, such as injuries or long-term disabilities, can result in people receiving physical assistance while in bed. We present a robotic system for bedside assistance that consists of a robotic bed and a mobile manipulator (i.e., a wheeled robot with arms) that work together to provide better assistance. Many assistive tasks depend on moving with respect to the person’s body, and the complementary physical and perceptual capabilities of the two robots help with respect to this general goal. The system provides autonomy for common tasks, as well as an interface for direct teleoperation of the two robots. Autonomy handles coarse motions of the robots by estimating the person’s pose using a pressure sensing mat and then moving the robots to configurations optimized for the task. After completing these motions, the user is given fine control of the robots to complete the task. In an evaluation using a medical mannequin, we found that the robotic bed’s motion and perception each improved the assistive robotic system’s performance. The system achieved 100% success over 9 trials involving 3 tasks. Using the system with the bed movement or the body pose estimation capabilities turned off resulted in success in only 33% or 78% of the trials, respectively. We also evaluated our system with Henry Evans, a person with severe quadriplegia, in his home. In a formal test, Henry successfully used the bedside-assistance system to perform 3 different tasks, 5 times each, without any failures. Henry’s feedback on the system was positive regarding usefulness and ease of use, and he noted benefits of using our system over fully manual teleoperation. Overall, our results suggest that a robotic bed and a mobile manipulator can work collaboratively to provide effective personal assistance and that the combination of the two robots is beneficial.