In-Hospital Initiation of Lipid-Lowering Therapy for Patients With Coronary Heart Disease

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

“…Thus, there appear to be no adverse effects and substantial advantages to the initiation of lipid-lowering therapy before hospital discharge. 652,654 Such early initiation of therapy also has been recommended in the update of the third report of the NCEP. 16 Adherence to statin therapy was shown to be associated with improved survival in a large, population-based longitudinal observational study.…”

ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

“…In a demonstration project, the Cardiovascular Hospitalization Atherosclerosis Management Program, the in-hospital initiation of lipid-lowering therapy increased the percentage of patients treated with statins 1 year later from 10% to 91%, and for those with an LDL-C less than 100 mg per dL, the percentage increased from 6% to 58% (653), which suggests that predischarge initiation of lipid-lowering therapy enhances long-term compliance. Thus, there appear to be no adverse effects and substantial advantages to the initiation of lipid-lowering therapy before hospital discharge (652,654). Such early initiation of therapy also has been recommended in the update of the third report of the NCEP (16).…”

2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

“…Thus, there appear to be no adverse effects and substantial advantages to the initiation of lipid-lowering therapy before hospital discharge. 756,758 Such early initiation of therapy also has been recommended in the update of the third report of the NCEP. 23 Adherence to statin therapy was shown to be associated with improved survival in a large, population-based longitudinal observational study.…”