Introduction/Objective. Even with the current treatment mortality from aortic
dissection remains high. The study aimed to evaluate the early postoperative
outcome of patients with aortic dissection and identify which factors could
have influence on it. Methods. The study included all consecutive patients
who underwent surgery for acute aortic dissection type A from 2012 to 2017.
We registered all parameters that could potentially impact the outcome
(general data, medical history, clinical and cardiological diagnostic test
findings, preoperative complications, type of cannulation and the operation
performed, additional surgical procedures, operation duration, etc.).
Patients were surgically treated according to the current protocols. The
main outcome measures were complications and mortality during a one-month
postoperative period. All data collected pre-, intra-, and postoperatively
were compared and statistically analyzed. Results. The study included 246
patients, of an average 57.54+/-12.88 years of age and mostly male sex
(74%). Early postoperative mortality occurred in 17% of patients.
Preoperative chronic kidney insufficiency (p = 0.005) and cerebrovascular
insult (p = 0.047) and tamponade (p = 0.036) were the major risk factors for
postoperative complications and mortality. Long hypothermic cardiac arrest
(p = 0.001), cross clamp (p = 0.017) and cardiopulmonary bypass time (p =
0.036) increased postoperative complications. Postoperative complications
started occurring after ?33.5 minutes hypothermic cardiac arrest and ?67.5
minutes cross clamp time. Having more postoperative complications (p =
0.034) increased, while performing anterograde cerebral perfusion decreased
the frequency of lethal outcome (p = 0.001). Conclusion. The majority of
patients surgically treated for acute aortic dissection had good
postoperative outcome. However, numerous pre-, intra- and postoperative
factors can impact patient survival.