In Operando Imaging Electrostatic-Driven Disassembly and Reassembly of Collagen Nanostructures
Clara Garcia-Sacristan,
Victor G. Gisbert,
Kevin Klein
et al.
Abstract:Collagen is the most abundant protein in tissue scaffolds in live organisms. Collagen can self-assemble in vitro, which has led to a number of biotechnological and biomedical applications. To understand the dominant factors that participate in the formation of collagen nanostructures, here we study in real time and with nanoscale resolution the disassembly and reassembly of collagens. We implement a high-speed force microscope, which provides in situ high spatiotemporal resolution images of collagen nanostruct… Show more
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