In-Patient Treatment of Fibromyalgia: A Controlled Nonrandomized Comparison of Conventional Medicine versus Integrative Medicine including Fasting Therapy

Michalsen, Andreas; Li, Chenying; Kaiser, Katharina; Lüdtke, Rainer; Meier, Larissa; Stange, Rainer; Kessler, Christian S.

doi:10.1155/2013/908610

Cited by 38 publications

(42 citation statements)

References 29 publications

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“…After the removal of duplicates, a total of 7080 studies was identified in the search. Following full‐text screening, 71 studies were identified for inclusion, with 23 eligible for meta‐analysis. The abstracts for the majority of the papers were not sufficiently detailed to determine whether the full text should be retrieved.…”

Section: Resultsmentioning

confidence: 99%

A systematic review and meta‐analysis of nutrition interventions for chronic noncancer pain

Brain

Burrows

Rollo

et al. 2018

J Human Nutrition Diet

141

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Background: This systematic review aimed to evaluate the impact of nutrition interventions on participant reported pain severity and intensity in populations with chronic pain. Methods: Eight databases were systematically searched for studies that included adult populations with a chronic pain condition, a nutrition intervention and a measure of pain. Where possible, data were pooled using meta-analysis. Seventy-one studies were included, with 23 being eligible for meta-analysis. Results: Studies were categorised into four groups: (i) altered overall diet with 12 of 16 studies finding a significant reduction in participant reported pain; (ii) altered specific nutrients with two of five studies reporting a significant reduction in participant reported pain; (iii) supplement-based interventions with 11 of 46 studies showing a significant reduction in pain; and (iv) fasting therapy with one of four studies reporting a significant reduction in pain. The meta-analysis found that, overall, nutrition interventions had a significant effect on pain reduction with studies testing an altered overall diet or just one nutrient having the greatest effect. Conclusions: This review highlights the importance and effectiveness of nutrition interventions for people who experience chronic pain.198

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Section: Resultsmentioning

confidence: 99%

A systematic review and meta‐analysis of nutrition interventions for chronic noncancer pain

Brain

Burrows

Rollo

et al. 2018

J Human Nutrition Diet

141

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“…Furthermore, results of a controlled trial [91] suggested fasting therapy to be beneficial compared to normocaloric diet in the complex treatment of fibromyalgia. In a further controlled nonrandomized trial [92], we found a beneficial effect of fasting over standard complex treatment in inpatients with fibromyalgia. An uncontrolled study from Germany [62] reported a beneficial effect of fasting on headache frequency and intensity of migraine.…”

Section: Clinical Effects Of Fastingmentioning

confidence: 97%

Fasting Therapy for Treating and Preventing Disease - Current State of Evidence

Michalsen

2013

Complement Med Res

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114

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Periods of deliberate fasting with restriction of solid food intake are practiced worldwide, mostly based on traditional, cultural or religious reasons. There is large empirical and observational evidence that medically supervised modified fasting (fasting cure, 200-500 kcal nutritional intake per day) with periods of 7-21 days is efficacious in the treatment of rheumatic diseases, chronic pain syndromes, hypertension, and metabolic syndrome. The beneficial effects of fasting followed by vegetarian diet in rheumatoid arthritis are confirmed by randomized controlled trials. Further beneficial effects of fasting are supported by observational data and abundant evidence from experimental research which found caloric restriction and intermittent fasting being associated with deceleration or prevention of most chronic degenerative and chronic inflammatory diseases. Intermittent fasting may also be useful as an accompanying treatment during chemotherapy of cancer. A further beneficial effect of fasting relates to improvements in sustainable lifestyle modification and adoption of a healthy diet, possibly mediated by fasting-induced mood enhancement. Various identified mechanisms of fasting point to its potential health-promoting effects, e.g., fasting-induced neuroendocrine activation and hormetic stress response, increased production of neurotrophic factors, reduced mitochondrial oxidative stress, general decrease of signals associated with aging, and promotion of autophagy. Fasting therapy might contribute to the prevention and treatment of chronic diseases and should be further evaluated in controlled clinical trials and observational studies.

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“…There is preliminary evidence from smaller nonrandomized controlled trials or observational studies for metabolic syndrome [30,31,32,33,34,][50], osteoarthritis [35], fibromyalgia [36], hypertension [37,38,39], chronic pain syndromes of the locomotor system [23,40], migraine [41], enhancement of lifestyle change [42,8] and psychological well-being, support of chemotherapy [43,44], and mood-enhancement [23,45]. …”

Section: Indicationsmentioning

confidence: 99%

Fasting Therapy - an Expert Panel Update of the 2002 Consensus Guidelines

Buchinger²,

et al. 2013

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Fasting for medical purpose (fasting therapy) has a long tradition in Europe and is established as a defined therapeutic approach in specialized fasting hospitals or within clinical departments for integrative medicine. In 2002, the first guidelines for fasting therapy were published following an expert consensus conference; here we present a revised update elaborated by an expert panel. Historical aspects and definitions, indications, methods, forms, and accompanying procedures of fasting as well as safety and quality criteria of fasting interventions are described. Fasting has shown beneficial effects in various chronic diseases with highest level of evidence for rheumatic diseases. Preliminary clinical and observational data and recently revealed mechanisms of fasting and caloric restriction indicate beneficial effects of fasting also in other chronic conditions such as metabolic diseases, pain syndromes, hypertension, chronic inflammatory diseases, atopic diseases, and psychosomatic disorders. Fasting can also be applied for preventing diseases in healthy subjects. In order to guarantee successful use of fasting and to ensure adherence of all safety and quality standards it is mandatory that all interventions during fasting are guided/accompanied by physicians/therapists trained and certified in fasting therapy.

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In-Patient Treatment of Fibromyalgia: A Controlled Nonrandomized Comparison of Conventional Medicine versus Integrative Medicine including Fasting Therapy

Cited by 38 publications

References 29 publications

A systematic review and meta‐analysis of nutrition interventions for chronic noncancer pain

A systematic review and meta‐analysis of nutrition interventions for chronic noncancer pain

Fasting Therapy for Treating and Preventing Disease - Current State of Evidence

Fasting Therapy - an Expert Panel Update of the 2002 Consensus Guidelines

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