In-Phase Bias Modulation Mode of Scanning Ion Conductance Microscopy With Capacitance Compensation

Li, Peng; Liu, Lianqing; Yang, Yang; Wang, Yuechao; Li, Guangyong

doi:10.1109/tie.2015.2417126

Cited by 18 publications

(13 citation statements)

References 32 publications

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“…However, this isotonic solution cannot serve as a cell culture solution and the cells can only remain active for several minutes. Although this isotonic solution has no negative effect on the application of AC electrokinetic-based microfluidics in bio-related fields, it may impede the integration of this mechanism with other fashionable micro/nano-robotic manipulation tools-such as AFM [107][108][109], scanning ion conductance microscopy [110][111][112], and acoustic tweezers [113][114][115]-to rapidly and simultaneously acquire the intrinsic properties of cells. The integration of DEP with AFM was demonstrated to be capable of manipulating and assembling nanoparticles accurately [116][117][118].…”

Section: Conclusion and Prospectsmentioning

confidence: 99%

Determination of Dielectric Properties of Cells using AC Electrokinetic-based Microfluidic Platform: A Review of Recent Advances

Yang

Wang

et al. 2020

Micromachines

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Cell dielectric properties, a type of intrinsic property of cells, can be used as electrophysiological biomarkers that offer a label-free way to characterize cell phenotypes and states, purify clinical samples, and identify target cancer cells. Here, we present a review of the determination of cell dielectric properties using alternating current (AC) electrokinetic-based microfluidic mechanisms, including electro-rotation (ROT) and dielectrophoresis (DEP). The review covers theoretically how ROT and DEP work to extract cell dielectric properties. We also dive into the details of differently structured ROT chips, followed by a discussion on the determination of cell dielectric properties and the use of these properties in bio-related applications. Additionally, the review offers a look at the future challenges facing the AC electrokinetic-based microfluidic platform in terms of acquiring cell dielectric parameters. Our conclusion is that this platform will bring biomedical and bioengineering sciences to the next level and ultimately achieve the shift from lab-oriented research to real-world applications.

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Section: Conclusion and Prospectsmentioning

confidence: 99%

Determination of Dielectric Properties of Cells using AC Electrokinetic-based Microfluidic Platform: A Review of Recent Advances

Yang

Wang

et al. 2020

Micromachines

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“…As this method evolves over time, researchers have recognized the importance of integrating OEK with other devices/ tools to detect, analyze, and measure micro/nano-objects for biomedical and tissue engineering applications. This requires systematically combining OEK chips with other predominant micro/ nanorobotic-based techniques, such as atomic force microscopy, 119 acoustics tweezers, 120 and scanning ion conductance microscopy, 121 to achieve efficient 3D manipulation and multiparameter simultaneous acquisition, detection, and analysis of single cells.…”

Section: Challenges and Prospectsmentioning

confidence: 99%

Optoelectrokinetics-based microfluidic platform for bioapplications: A review of recent advances

et al. 2019

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The introduction of optoelectrokinetics (OEK) into lab-on-a-chip systems has facilitated a new cutting-edge technique-the OEK-based micro/nanoscale manipulation, separation, and assembly processes-for the microfluidics community. This technique offers a variety of extraordinary advantages such as programmability, flexibility, high biocompatibility, low-cost mass production, ultralow optical power requirement, reconfigurability, rapidness, and ease of integration with other microfluidic units. This paper reviews the physical mechanisms that govern the manipulation of micro/nano-objects in microfluidic environments as well as applications related to OEK-based micro/nanoscale manipulation-applications that span from single-cell manipulation to single-molecular behavior determination. This paper wraps up with a discussion of the current challenges and future prospects for the OEK-based microfluidics technique. The conclusion is that this technique will allow more opportunities for biomedical and bioengineering researchers to improve lab-on-a-chip technologies and will have farreaching implications for biorelated researches and applications in the future.

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“…Up to now, these advancements can be briefly summarized as follows. The specific capacitance of carbon-based electrodes gets increasing as a novel carbon structure develops, with an extremely active specific surface area and a high packing density [13]. Pseudocapacitors based on pseudocapacitive materials is developing with high specific capacitance contributed from the pseudo-capacitance, such as some electroactive transition-metal oxides [14] and conducting polymers [15].…”

Section: Introductionmentioning

confidence: 99%

Recent progress in supercapacitors based on the advanced carbon electrodes

Pan

2019

Nanotechnology Reviews

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This paper demonstrates a brief review of the research progress of the advanced carbon-based materials for the supercapacitor electrodes. Diverse types of carbon-based electrodes exploited and reported to the literature are summarized and classified into pure carbon electrodes, carbon/metal oxides composite electrodes, carbon/metal oxides/conducting polymers composite electrodes as well as carbon electrodes based on other materials. Pure carbon electrodes are firstly introduced, confirming their merits and shortcomings. To cover the shortage of pure carbon electrodes and further enhances their electrochemical performance, a composite electrode, combined with metal oxides and conducting polymers, is respectively presented. It is worth noticing in this article that combining various materials to form composites has been one main direction to own a positive synergistic effect on the carbon-based electrodes.

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In-Phase Bias Modulation Mode of Scanning Ion Conductance Microscopy With Capacitance Compensation

Cited by 18 publications

References 32 publications

Determination of Dielectric Properties of Cells using AC Electrokinetic-based Microfluidic Platform: A Review of Recent Advances

Determination of Dielectric Properties of Cells using AC Electrokinetic-based Microfluidic Platform: A Review of Recent Advances

Optoelectrokinetics-based microfluidic platform for bioapplications: A review of recent advances

Recent progress in supercapacitors based on the advanced carbon electrodes

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