In Response to the Letter to the Editor Regarding “Acute Hemorrhage After Intra-cerebral Biopsy in COVID-19 Patients: A Report of 3 Cases”

Degeneffe, Aurélie; Witte, Olivier De; Lubansu, Alphonse

doi:10.1016/j.wneu.2020.07.045

Cited by 4 publications

(6 citation statements)

References 11 publications

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“…In critically ill patients, COVID-19 has been associated with coagulopathies such as DIC, thrombocytopenia, elevated D-dimer, and prolonged prothrombin time which can result in hemorrhage. [113] Another potential mechanism is the effect of SARS-CoV-2 on ACE2. As mentioned earlier, SARS-CoV-2 has been shown to use the ACE 2 receptor for cell entry.…”

Section: Cerebrovascular Events Acute Ischemic Stroke(ais) Has Beenmentioning

confidence: 99%

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Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic

Dorche

Huot

Osherov

et al. 2020

Journal of the Neurological Sciences

186

182

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Coronavirus disease-19 (COVID-19) pandemic continues to grow all over the world. Several studies have been performed, focusing on understanding the acute respiratory syndrome and treatment strategies. However, there is growing evidence indicating neurological manifestations occur in patients with COVID-19. Similarly, the other coronaviruses (CoV) epidemics; severe acute respiratory syndrome (SARS-CoV-1) and Middle East respiratory syndrome (MERS-CoV) have been associated with neurological complications. Methods: This systematic review serves to summarize available information regarding the potential effects of different types of CoV on the nervous system and describes the range of clinical neurological complications that have been reported thus far in COVID-19. Results: Two hundred and twenty-five studies on CoV infections associated neurological manifestations in human were reviewed. Of those, 208 articles were pertinent to COVID-19. The most common neurological complaints in COVID-19 were anosmia, ageusia, and headache, but more serious complications, such as stroke, impairment of consciousness, seizures, and encephalopathy, have also been reported. Conclusion: There are several similarities between neurological complications after SARS-CoV-1, MERS-CoV and COVID-19, however, the scope of the epidemics and number of patients are very different. Reports on the neurological complications after and during COVID-19 are growing on a daily basis. Accordingly, comprehensive knowledge of these complications will help health care providers to be attentive to these complications and diagnose and treat them timely.

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Section: Cerebrovascular Events Acute Ischemic Stroke(ais) Has Beenmentioning

confidence: 99%

“…There are reports that suggested even neurosurgical interventions were accompanied with more hemorrhagic complications in patients with COVID-19. [113] Cerebral Venous Sinus Thrombosis was reported in 13 patients out of 9 studies. (Table 3).…”

Section: Cerebrovascular Events Acute Ischemic Stroke(ais) Has Beenmentioning

confidence: 99%

Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic

Dorche

Huot

Osherov

et al. 2020

Journal of the Neurological Sciences

186

182

View full text Add to dashboard Cite

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“…8 In another study the authors reported diffuse intraparenchymal hemorrhage in 3 COVID-19 patients who underwent diagnostic intracerebral biopsy. 9 Authors in this study hypothesized that active COVID-19 infection might predispose to increased risk of bleeding. 9 Hydroxychloroquine has also been used extensively during this pandemic.…”

Section: Covid-19 and Treatment-related Cerebrovascular Eventsmentioning

confidence: 95%

“…9 Authors in this study hypothesized that active COVID-19 infection might predispose to increased risk of bleeding. 9 Hydroxychloroquine has also been used extensively during this pandemic. It has been shown to reduce the rates of acute myocardial infarction and cerebrovascular events in prior studies.…”

Section: Covid-19 and Treatment-related Cerebrovascular Eventsmentioning

confidence: 95%

Letter to the Editor Regarding “Acute Stroke Management During the Coronavirus Disease 2019 (COVID-19) Pandemic: From Trough of Disillusionment to Slope of Enlightenment”

2020

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Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre-including this research content-immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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“…The patient died after 3 days due to COVID-19-related complications, and no further clinical evaluations were performed (29). In another case report from a hospital in Belgium, 3 out of 31 patients with advance tumorlike brain lesions, tested positive with SARS-CoV-2 (30). All three patients suffered from diffuse intraparenchymal hemorrhage post-operatively, suggesting that an active infection may be related to a higher bleeding risk.…”

Section: Pathology Of Sars-cov-2 In the Cnsmentioning

confidence: 96%

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the Nervous System: Implications of COVID-19 in Neurodegeneration

et al. 2020

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Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2), began in December 2019, in Wuhan, China and was promptly declared as a pandemic by the World Health Organization (WHO). As an acute respiratory disease, COVID-19 uses the angiotensin-converting enzyme 2 (ACE2) receptor, which is the same receptor used by its predecessor, SARS-CoV, to enter and spread through the respiratory tract. Common symptoms of COVID-19 include fever, cough, fatigue and in a small population of patients, SARS-CoV-2 can cause several neurological symptoms. Neurological malaise may include severe manifestations, such as acute cerebrovascular disease and meningitis/encephalitis. Although there is evidence showing that coronaviruses can invade the central nervous system (CNS), studies are needed to address the invasion of SARS-CoV-2 in the CNS and to decipher the underlying neurotropic mechanisms used by SARS-CoV-2. This review summarizes current reports on the neurological manifestations of COVID-19 and addresses potential routes used by SARS-CoV-2 to invade the CNS.

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In Response to the Letter to the Editor Regarding “Acute Hemorrhage After Intra-cerebral Biopsy in COVID-19 Patients: A Report of 3 Cases”

Cited by 4 publications

References 11 publications

Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic

Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic

Letter to the Editor Regarding “Acute Stroke Management During the Coronavirus Disease 2019 (COVID-19) Pandemic: From Trough of Disillusionment to Slope of Enlightenment”

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the Nervous System: Implications of COVID-19 in Neurodegeneration

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