In search for the optimal ventricular systolic dysfunction metric that associates with reduced exercise capacity

Early echocardiographic and electrophysiological characteristics of subclinical hyperthyroidism

“…For example, it was documented that EF is inversely associated with the sum of ESV and EDV, yielding R = −0.66 (for 96 cardiac patients) 6 . Additionally, it was shown that the interrelationship between EF, GLS and GCS can be analytically described, but yet requires consideration of a fourth component which metric is characterized by a physical unit, in contrast to the three dimensionless ratios involved 7 . In the study by Karaca et al 2 the abovementioned set of three ratio‐based metrics was enriched by including two additional ratios, namely GRS and GAS.…”

“…6 Additionally, it was shown that the interrelationship between EF, GLS and GCS can be analytically described, but yet requires consideration of a fourth component which metric is characterized by a physical unit, in contrast to the three dimensionless ratios involved. 7 In the study by Karaca et al 2 the abovementioned set of three ratio-based metrics was enriched by including two additional ratios, namely GRS and GAS. This approach yields a collection of five (individually) incomplete metrics.…”

Sex-Specific Evaluation of Arterial Stiffness and Left Ventricular Remodeling

“… 4 Also, the pressure-related term was shown to depend on age, and to differ for men and women, especially at younger ages. 3 Additionally, GLS depends not only on EF but also on circumferential strain 6 and on end-diastolic volume (EDV), 7 meaning that this metric (when used in isolation) provides incomplete information.…”