In silico analysis of PirA- and PirB-like toxin genes of Vibrio spp., present in Asia and Costa Rica

What Happened Over the Last 10 Years (2012 to 2021): A Bibliometric Analysis of Acute Hepatopancreatic Necrosis Disease (AHPND) Research in Southeast Asia

“…This is in agreement with the results of the overlay visualization of keywords performed via VOSviewer version 1.6.17 (Figure 9) wherein early researches on AHPND focused on the characterization of the bacterial causative agent and its plasmid, development of detection protocols via polymerase chain reaction (PCR), loop-mediated isothermal amplification (LAMP), and histopathological analyses. As shown in Figure 9, recent advances in AHPND research in Southeast Asia include the characterization of non-Vibrio parahaemolyticus species as causative agents of AHPND (De Guia et al, 2020;Dong et al, 2017;Muthukrishnan et al, 2019). As time progressed, research on AHPND focused on combating the disease (Santos et al, 2020), immune response of shrimp against AHPND upon supplementation with immunostimulants (Alonzo et al, 2017;Arabit et al, 2017), generation of polyclonal antibodies (Nguyen-Phuoc et al, 2021), the role of quorum sensing (Paopradit et al, 2021), and the use of bioactive compounds to target the mechanisms involved in the pathogenesis of AHPND (Dadi et al, 2021;Guzman et al, 2021;Karnjana et al, 2019Karnjana et al, , 2020Nguyen Thi Truc et al, 2019;Soowannayan, Boonmee, et al, 2019;Soowannayan, Chandra Teja, et al, 2019;Yatip et al, 2018).…”