in silico Computational Studies of phenolic compounds from Pinaropappus roseus Less leaves extract against BCL-2 and BCL-XL proteins Associated with Cancer Cell Survival and Resistance
Juan Camilo Tejeda-Orjuela,
Irene Chaparro-Hernández,
Lilia Leticia Mendez-Lagunas
et al.
Abstract:The aim of this study was to investigate the phenolic compound from Pinaropappus roseus, and its human breast anticancer properties. The phenolic molecules were isolated from the aqua-ethanoic extract isolated from the leaves of P. roseus by solid-phase extraction (SPE). The total phenolic content was determined by the Folin-Ciocalteu technique. The profile of phenolic compounds was analyzed by mass spectrometry (LC-ESI-MS2). The quantification of phenolic molecules identified by mass spectrometry was carried … Show more
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