2024
DOI: 10.3389/fphar.2024.1358037
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In silico identification of compounds from Piper sarmentosum Roxb leaf fractionated extract inhibit interleukin-6 to prevent rheumatoid arthritis

Tran Nhat Phong Dao,
Sunday Amos Onikanni,
Adewale Oluwaseun Fadaka
et al.

Abstract: Objective: Medicinal herbs with a phytonutrient background has been applied globally as major alternatives to ameliorate the continuous increase in rheumatoid arthritis cases worldwide. We herein aimed to critically examine the bioactive components of the medicinal herb Piper sarmentosum Roxb leaf fractionated extract for its potential to inhibit the influx of interleukin-6 (IL-6) in rheumatoid arthritis.Methods: The Schrödinger platform was employed as the main computational acumen for the screening of bioact… Show more

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